Viruses and autoimmunity: a review on the potential interaction and molecular mechanisms

MK Smatti, FS Cyprian, GK Nasrallah, AA Al Thani… - Viruses, 2019 - mdpi.com
For a long time, viruses have been shown to modify the clinical picture of several
autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus …

Virus infection, antiviral immunity, and autoimmunity

DR Getts, EML Chastain, RL Terry… - Immunological …, 2013 - Wiley Online Library
As a group of disorders, autoimmunity ranks as the third most prevalent cause of morbidity
and mortality in the W estern W orld. However, the etiology of most autoimmune diseases …

Virus-induced autoimmunity: potential role of viruses in initiation, perpetuation, and progression of T-cell–mediated autoimmune disease

JK Olson, JL Croxford, SD Miller - Viral immunology, 2001 - liebertpub.com
Virus infections have been implicated in the initiation of multiple human autoimmune
diseases. This article focuses on reviewing the role of viruses in initiation, progression, and …

Viruses, host responses, and autoimmunity

MS Horwitz, N Sarvetnick - Immunological reviews, 1999 - Wiley Online Library
Conceptually, the initiation of autoimmune disease can be described as a three‐stage
process involving both genetic and environmental influences. This process begins with the …

The role of viral infections in the development of autoimmune diseases

HM Hussein, EA Rahal - Critical reviews in microbiology, 2019 - Taylor & Francis
The exact aetiology of most autoimmune diseases remains unknown, nonetheless, several
factors contributing to the induction or exacerbation of autoimmune reactions have been …

Virus-induced autoimmune disease

MG von Herrath, MBA Oldstone - Current opinion in immunology, 1996 - Elsevier
The braking of tolerance or unresponsiveness to self-antigens, involving the activation of
autoreactive lymphocytes, is a critical event leading to autoimmune diseases. The precise …

Viral triggers for autoimmunity: is the 'glass of molecular mimicry'half full or half empty?

U Christen, E Hintermann, M Holdener… - Journal of …, 2010 - Elsevier
In this review we want to consider some of the requirements for autoimmune disease to
develop and how this may be reproduced in animal models. Besides a genetic …

The role of viral infections in the onset of autoimmune diseases

B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Virus-induced autoimmunity

A Schattner, B Rager-Zisman - Reviews of infectious diseases, 1990 - academic.oup.com
Viral infections in humans commonly result in the transient appearance of a variety of
autoantibodies and, in some patients, the development of autoimmune tissue injury and …

Infectious diseases and autoimmunity

LG Delogu, S Deidda, G Delitala, R Manetti - The Journal of Infection in …, 2011 - jidc.org
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host
tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria …