[HTML][HTML] HIV infection and the gastrointestinal immune system
JM Brenchley, DC Douek - Mucosal immunology, 2008 - Elsevier
There has recently been a resurgence of interest in the gastrointestinal pathology observed
in patients infected with HIV. The gastrointestinal tract is a major site of HIV replication …
in patients infected with HIV. The gastrointestinal tract is a major site of HIV replication …
Pathogenesis of HIV in the gastrointestinal tract
S Dandekar - Current HIV/AIDS Reports, 2007 - Springer
Gut-associated lymphoid tissue (GALT) is an important site for early HIV replication and
severe CD4+ T-cell depletion. Initiation of highly active antiretroviral therapy leads to …
severe CD4+ T-cell depletion. Initiation of highly active antiretroviral therapy leads to …
Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis
Our results show that impairment of the gastrointestinal tracts in human immunodeficiency
virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is …
virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is …
The gastrointestinal tract and AIDS pathogenesis
Gastrointestinal disease has been recognized as a major manifestation of human
immunodeficiency virus infection since the earliest recognition of acquired …
immunodeficiency virus infection since the earliest recognition of acquired …
The mucosal barrier and immune activation in HIV pathogenesis
JM Brenchley, DC Douek - Current Opinion in HIV and AIDS, 2008 - journals.lww.com
The mucosal barrier and immune activation in HIV pathogenesi... : Current Opinion in HIV and
AIDS The mucosal barrier and immune activation in HIV pathogenesis : Current Opinion in HIV …
AIDS The mucosal barrier and immune activation in HIV pathogenesis : Current Opinion in HIV …
Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals
SN Gordon, B Cervasi, P Odorizzi… - The Journal of …, 2010 - journals.aai.org
HIV infection is associated with depletion of intestinal CD4+ T cells, resulting in mucosal
immune dysfunction, microbial translocation, chronic immune activation, and progressive …
immune dysfunction, microbial translocation, chronic immune activation, and progressive …
[PDF][PDF] The mucosal immune system and HIV-1 infection
Recent progress in HIV-1 and SIV pathogenesis has revealed that mucosal tissues, primarily
the gastrointestinal tract, are major sites for early viral replication and CD4+ T-cell …
the gastrointestinal tract, are major sites for early viral replication and CD4+ T-cell …
Acute HIV infection induces mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a mucosal barrier defect
HJ Epple, K Allers, H Tröger, A Kühl, U Erben… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: A barrier defect of the intestinal mucosa is thought to affect the
progression of human immunodeficiency virus (HIV) infection. It is not clear whether the …
progression of human immunodeficiency virus (HIV) infection. It is not clear whether the …
Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4+ T Lymphocytes from Effector Sites in the Gastrointestinal Tract
S Mehandru, MA Poles, K Tenner-Racz… - The Journal of …, 2004 - rupress.org
Given its population of CCR5-expressing, immunologically activated CD4+ T cells, the
gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV) …
gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV) …
[HTML][HTML] Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels
EJ Ciccone, SW Read, PJ Mannon, MD Yao… - Mucosal …, 2010 - Elsevier
The gut mucosa is an important site of HIV immunopathogenesis with severe depletion of
CD4+ T cells occurring during acute infection. The effect of prolonged anti-retroviral therapy …
CD4+ T cells occurring during acute infection. The effect of prolonged anti-retroviral therapy …