In silico design of a TLR4-mediating multiepitope chimeric vaccine against amyotrophic lateral sclerosis via advanced immunoinformatics

K Saleki, MH Mohamadi, M Banazadeh… - Journal of Leukocyte …, 2022 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is the most prevalent motor neuron disorder worldwide.
In ALS, progressing disease can result from misfolding and aggregation of superoxide …

Immunoinformatics-aided design of a potential multi-epitope peptide vaccine against Leishmania infantum

B Vakili, M Eslami, GR Hatam, B Zare, N Erfani… - International journal of …, 2018 - Elsevier
Visceral leishmaniasis (VL) or kala-azar, the most severe form of the disease, is endemic in
more than eighty countries across the world. To date, there is no approved vaccine against …

In silico and immunoinformatics based multiepitope subunit vaccine design for protection against visceral leishmaniasis

D Bhowmik, A Bhuyan, S Gunalan… - Journal of …, 2023 - Taylor & Francis
Visceral leishmaniasis (VL) is a vector-borne neglected tropical protozoan disease with high
fatality and no certified vaccine. Conventional vaccine preparation is challenging and …

Design of a multi-epitope subunit vaccine for immune-protection against Leishmania parasite

S Yadav, J Prakash, H Shukla, KC Das… - Pathogens and global …, 2020 - Taylor & Francis
Visceral Leishmaniasis (VL) is an insect-borne neglected disease caused by the protozoan
parasite Leishmania donovani. In the absence of a commercial vaccine against VL …

Immunoinformatics approach to design a multi-epitope vaccine against cutaneous leishmaniasis

S Naz, A Aroosh, A Caner, EA Şahar, S Toz, Y Ozbel… - Vaccines, 2023 - mdpi.com
Cutaneous Leishmaniasis (CL), a neglected vector-borne disease caused by protozoan
parasite Leishmania major (L. major), is a major public health concern, and the development …

In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovani

S Saha, S Vashishtha, B Kundu, M Ghosh - BMC bioinformatics, 2022 - Springer
Abstract Background Visceral Leishmaniasis (VL) is a fatal vector-borne parasitic disorder
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …

In silico designing a novel TLR4-mediating multiepitope vaccine against monkeypox via advanced immunoinformatics and bioinformatics approaches

MR Lahimchi, H Madanchi, K Ahmadi… - Journal of …, 2024 - Taylor & Francis
Monkeypox virus is a member of the Poxviridae family, which causes monkeypox zoonotic
disease. Since July 2022, the prevention of monkeypox have become more considerable …

Immunoinformatics approach to design a novel subunit vaccine against visceral leishmaniasis

A Lari, N Lari, A Biabangard - International Journal of Peptide Research …, 2022 - Springer
Visceral leishmaniasis (VL) infection is mostly caused by Leishmania donovani and affects
countries worldwide. Despite the need for a safe and effective vaccine against leishmaniasis …

[HTML][HTML] Employing an immunoinformatics approach revealed potent multi-epitope based subunit vaccine for lymphocytic choriomeningitis virus

M Waqas, S Aziz, A Bushra, SA Halim, A Ali… - Journal of Infection and …, 2023 - Elsevier
Background Lymphocytic choriomeningitis virus (LCMV) infects many individuals worldwide
and causes severe infection in the immunosuppressant recipient, spontaneous abortion …

Structural vaccinology considerations for in silico designing of a multi-epitope vaccine

M Negahdaripour, N Nezafat, M Eslami… - Infection, Genetics and …, 2018 - Elsevier
Multi-epitope peptide vaccines, as a kind of fusion proteins, usually possess a string-of-
beads structure, consisting of several peptidic epitopes, probably adjuvants and linkers …