Production of High Hydroxytyrosol Yields via Tyrosol Conversion by Pseudomonas aeruginosa Immobilized Resting Cells

Z Bouallagui, S Sayadi - Journal of agricultural and food chemistry, 2006 - ACS Publications
An immobilized whole cell system was successfully performed to produce the most powerful
antioxidant, hydroxytyrosol. Bioconversion of tyrosol into hydroxytyrosol was achieved via …

Use of Whole Cells of Pseudomonas aeruginosa for Synthesis of the Antioxidant Hydroxytyrosol via Conversion of Tyrosol

N Allouche, M Damak, R Ellouz… - Applied and …, 2004 - Am Soc Microbiol
For the first time, a soil bacterium, designated Pseudomonas aeruginosa, was isolated
based on its ability to grow on tyrosol as a sole source of carbon and energy. During growth …

A Novel Microbial Consortia Catalysis Strategy for the Production of Hydroxytyrosol from Tyrosine

P Gong, J Tang, J Wang, C Wang, W Chen - International Journal of …, 2023 - mdpi.com
Hydroxytyrosol, a valuable plant-derived phenolic compound, is increasingly produced from
microbial fermentation. However, the promiscuity of the key enzyme HpaBC, the two …

Tyrosol to hydroxytyrosol biotransformation by immobilised cell extracts of Pseudomonas putida F6

SJ Brooks, EM Doyle, KE O'Connor - Enzyme and microbial technology, 2006 - Elsevier
Cell extracts of Pseudomonas putida F6 expressing tyrosinase activity were immobilised in a
calcium alginate matrix. Immobilised cell extracts consumed 21% more tyrosol substrate (2.5 …

Bioconversion of p‐Tyrosol into Hydroxytyrosol under Bench‐Scale Fermentation

Z Bouallagui, S Sayadi - BioMed Research International, 2018 - Wiley Online Library
Tyrosol hydroxylating Pseudomonas strain was previously isolated from olive mill
wastewaters‐irrigated soil. In the present work, experimental design was used to study the …

Engineering Eschericha coli for Enhanced Tyrosol Production

Y Xue, X Chen, C Yang, J Chang… - Journal of agricultural …, 2017 - ACS Publications
Tyrosol is a phenolic compound found in olive oil and wines. The health benefits of tyrosol
have attracted considerable attention. Because the tyrosol extraction from plants poses a …

The antioxidant hydroxytyrosol: Biotechnological production challenges and opportunities

Y Achmon, A Fishman - Applied microbiology and biotechnology, 2015 - Springer
Hydroxytyrosol (HT) is a highly potent antioxidant originating in nature as a second
metabolite of plants, most abundantly in olives (Olea europaea). In the last decade …

High-Level Production of Tyrosol with Noninduced Recombinant Escherichia coli by Metabolic Engineering

W Xu, C Yang, Y Xia, L Zhang, C Liu… - Journal of agricultural …, 2020 - ACS Publications
Tyrosol is a pharmacologically active phenolic compound widely used in the pharmaceutical
and chemical industries. Microbial fermentation has potential value as an environmentally …

De novo biosynthesis of tyrosol acetate and hydroxytyrosol acetate from glucose in engineered Escherichia coli

D Guo, X Fu, Y Sun, X Li, H Pan - Enzyme and Microbial Technology, 2021 - Elsevier
Tyrosol and hydroxytyrosol derived from virgin olive oil and olives extract, have wide
applications both as functional food components and as nutraceuticals. However, they have …

Synthesis of Hydroxytyrosol, 2-Hydroxyphenylacetic Acid, and 3-Hydroxyphenylacetic Acid by Differential Conversion of Tyrosol Isomers Using Serratia marcescens  …

N Allouche, S Sayadi - Journal of Agricultural and Food Chemistry, 2005 - ACS Publications
We investigated to develop an effective procedure to produce the potentially high-added-
value phenolic compounds through bioconversion of tyrosol isomers. A soil bacterium …