Biomarker testing for patients with advanced non–small cell lung cancer: real-world issues and tough choices

NA Pennell, ME Arcila, DR Gandara… - American Society of …, 2019 - ascopubs.org
Over the last decade, the treatment of patients with advanced non–small cell lung cancer
(NSCLC) has become reliant on tissue and/or blood biomarkers to help guide treatment …

[HTML][HTML] A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of non-small cell lung cancer

PM Ellis, N Blais, D Soulieres, DN Ionescu… - Journal of Thoracic …, 2011 - Elsevier
Introduction Greater understanding of molecular pathways important in cell growth and
proliferation of thoracic malignancies, particularly non-small cell lung cancer (NSCLC), has …

[HTML][HTML] Diagnostic, predictive, and prognostic biomarkers in non-small cell lung cancer (NSCLC) management

M Šutić, A Vukić, J Baranašić, A Försti… - Journal of personalized …, 2021 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths worldwide. Despite growing
efforts for its early detection by screening populations at risk, the majority of lung cancer …

Precision medicine in non-small cell lung cancer: Current applications and future directions

SR Yang, AM Schultheis, H Yu, D Mandelker… - Seminars in cancer …, 2022 - Elsevier
Advances in biomarkers, targeted therapies, and immuno-oncology have transformed the
clinical management of patients with advanced NSCLC. For oncogene-driven tumors, there …

Acquiring tissue for advanced lung cancer diagnosis and comprehensive biomarker testing: A National Lung Cancer Roundtable best‐practice guide

AH Fox, M Nishino, RU Osarogiagbon… - CA: A Cancer …, 2023 - Wiley Online Library
Advances in biomarker‐driven therapies for patients with nonsmall cell lung cancer
(NSCLC) both provide opportunities to improve the treatment (and thus outcomes) for …

Defining comprehensive biomarker‐related testing and treatment practices for advanced non‐small‐cell lung cancer: results of a survey of US oncologists

KF Mileham, C Schenkel, SS Bruinooge… - Cancer …, 2022 - Wiley Online Library
Background An ASCO taskforce comprised of representatives of oncology clinicians, the
American Cancer Society National Lung Cancer Roundtable (NLCRT), LUNGevity, the GO2 …

[HTML][HTML] Future perspective for the application of predictive biomarker testing in advanced stage non-small cell lung cancer

VD de Jager, W Timens, A Bayle, J Botling… - The Lancet Regional …, 2024 - thelancet.com
For patients with advanced stage non-small cell lung cancer (NSCLC), treatment strategies
have changed significantly due to the introduction of targeted therapies and immunotherapy …

[HTML][HTML] The evolving landscape of biomarker testing for non-small cell lung cancer in Europe

KM Kerr, F Bibeau, E Thunnissen, J Botling, A Ryška… - Lung Cancer, 2021 - Elsevier
The discovery of oncogenic driver mutations rendering non-small cell lung cancer (NSCLC)
targetable by small-molecule inhibitors, and the development of immunotherapies, have …

Molecular testing and targeted therapy for non-small cell lung cancer: current status and perspectives

EN Imyanitov, AG Iyevleva, EV Levchenko - Critical reviews in oncology …, 2021 - Elsevier
Molecular testing has become a mandatory component of the non-small cell lung cancer
(NSCLC) management. The detection of EGFR, BRAF and MET mutations as well as the …

Biomarkers in lung cancer

CR Sears, PJ Mazzone - Clinics in Chest Medicine, 2020 - chestmed.theclinics.com
Lung cancer is diagnosed in more than 1.8 million people yearly and remains the leading
cause of cancer deaths in both developing and developed countries, with survival at 5 years …