Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying
development, disease, and regeneration. As organoid research expands, the need for clear …

“Liver medicine” refers to all diagnostic and treatment strategies of diseases and conditions
that cause liver failure directly or indirectly. Despite significant advances in the field of liver …

The burden of liver diseases is increasing worldwide, with liver transplantation remaining
the only treatment option for end‐stage liver disease. Regenerative medicine holds great …

Organoids are three-dimensional culture systems in which adult stem cells and their
progeny grow and represent the native physiology of the cells in vivo. Organoids have been …

Organoid culture systems have emerged as a frontier technology in liver and biliary
research. These three‐dimensional (3D) cell cultures derived from pluripotent and adult …

Organoid cultures have emerged as an alternative in vitro system to recapitulate tissues in a
dish. While mouse models and cell lines have furthered our understanding of liver biology …

The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …

Liver cell types derived from induced pluripotent stem cells (iPSCs) share the potential to
investigate development, toxicity, as well as genetic and infectious disease in ways currently …

Background & Aims The development of hepatic models capable of long-term expansion
with competent liver functionality is technically challenging in a personalized setting. Stem …

Understanding the development, regeneration, and disorders of the liver is the major goal in
liver biology. Current mechanistic knowledge of human livers has been largely derived from …