Background & Aims Patient-derived organoid cancer models are generated from epithelial
tumor cells and reflect tumor characteristics. However, they lack the complexity of the tumor …

Patient-derived organoids (PDOs) serve as excellent tools for personalized drug screening
to predict clinical outcomes of cancer treatment. However, current methods for efficient …

As organ-specific three-dimensional cell clusters derived from cancer tissue or cancer-
specific stem cells, cancer-derived organoids are organized in the same manner of the cell …

Patient-derived xenograft (PDX) tumor model is a powerful technology in evaluating anti-
cancer drugs and facilitating personalized medicines. Multiple research centers and …

Cancer, which is a leading cause of death worldwide, places a big burden on health-care
system. In this study, an order-prediction model was built to predict a series of cancer drug …

Liver metastasis is a recalcitrant disease that usually leads to death of the patient. The
present study established a unique patient-derived orthotopic xenograft (PDOX) nude …

Since the introduction of chemotherapy for cancer treatment in the early 20th century
considerable efforts have been made to maximize drug efficiency and at the same time …

Opinion statement Though many advancements in personalized medicine have been made,
better methods are still needed to predict treatment benefit for patients with colorectal …

Cancer is a major health problem and a leading cause of death worldwide. Early cancer
detection and continuous changes in treatment strategies have improved overall patient …

Background Cancer is a highly heterogeneous disease with varying responses to anti-
cancer drugs. Although several attempts have been made to predict the anti-cancer …