[HTML][HTML] Predicting the artificial immunity induced by RUTI® vaccine against tuberculosis using universal immune system simulator (UISS)
Background Tuberculosis (TB) represents a worldwide cause of mortality (it infects one third
of the world's population) affecting mostly developing countries, including India, and recently …
of the world's population) affecting mostly developing countries, including India, and recently …
[HTML][HTML] Moving forward through the in silico modeling of tuberculosis: a further step with UISS-TB
Background In 2018, about 10 million people were found infected by tuberculosis, with
approximately 1.2 million deaths worldwide. Despite these numbers have been relatively …
approximately 1.2 million deaths worldwide. Despite these numbers have been relatively …
[HTML][HTML] Insight Into novel anti-tuberculosis vaccines by using immunoinformatics approaches
Tuberculosis (TB), an infectious disease, has been a leading cause of morbidity and
mortality for decades. The causative agent of TB is the Mycobacterium tuberculosis (Mtb) …
mortality for decades. The causative agent of TB is the Mycobacterium tuberculosis (Mtb) …
Tuberculosis: current status, diagnosis, treatment and development of novel vaccines
J Yadav, S Verma, D Chaudhary… - Current …, 2019 - ingentaconnect.com
Tuberculosis (TB) is an infectious disease that mainly affects the lungs and spreads to other
organs of the body through the haematogenous route. It is one of the ten major causes of …
organs of the body through the haematogenous route. It is one of the ten major causes of …
[HTML][HTML] An integrated computational framework to design a multi-epitopes vaccine against Mycobacterium tuberculosis
A Albutti - Scientific Reports, 2021 - nature.com
Tuberculosis (TB) is a highly contagious disease that mostly affects the lungs and is caused
by a bacterial pathogen, Mycobacterium tuberculosis. The associated mortality rate of TB is …
by a bacterial pathogen, Mycobacterium tuberculosis. The associated mortality rate of TB is …
[HTML][HTML] Generation of digital patients for the simulation of tuberculosis with UISS-TB
Abstract Background The STriTuVaD project, funded by Horizon 2020, aims to test through a
Phase IIb clinical trial one of the most advanced therapeutic vaccines against tuberculosis …
Phase IIb clinical trial one of the most advanced therapeutic vaccines against tuberculosis …
[HTML][HTML] In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology
Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …
[HTML][HTML] In silico agent-based modeling approach to characterize multiple in vitro tuberculosis infection models
In vitro models of Mycobacterium tuberculosis (Mtb) infection are a valuable tool for
examining host-pathogen interactions and screening drugs. With the development of more …
examining host-pathogen interactions and screening drugs. With the development of more …
[HTML][HTML] A Credibility Assessment Plan for an In Silico Model that Predicts the Dose–Response Relationship of New Tuberculosis Treatments
C Curreli, V Di Salvatore, G Russo… - Annals of Biomedical …, 2023 - Springer
Tuberculosis is one of the leading causes of death in several developing countries and a
public health emergency of international concern. In Silico Trials can be used to support …
public health emergency of international concern. In Silico Trials can be used to support …
In silico analysis of potential human T Cell antigens from Mycobacterium tuberculosis for the development of subunit vaccines against tuberculosis
S Devasundaram, A Deenadayalan… - Immunological …, 2014 - Taylor & Francis
In silico analysis was used to predict MHC class I and class II promiscuous epitopes and
potential antigens, from 24 novel T cell antigens of Mycobacterium tuberculosis. Majority of …
potential antigens, from 24 novel T cell antigens of Mycobacterium tuberculosis. Majority of …