Endothelial dysfunction and vascular disease–a 30th anniversary update

PM Vanhoutte, H Shimokawa, M Feletou… - Acta …, 2017 - Wiley Online Library
The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Endothelial dysfunction and vascular disease

PM Vanhoutte, H Shimokawa, EHC Tang… - Acta …, 2009 - Wiley Online Library
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

Endothelial dysfunction the first step toward coronary arteriosclerosis

PM Vanhoutte - Circulation Journal, 2009 - jstage.jst.go.jp
The endothelium causes relaxations of the underlying vascular smooth muscle, by releasing
nitric oxide (NO). The endothelial cells also can evoke hyperpolarization of the vascular …

Endothelial dysfunction and atherosclerosis

PM Vanhoutte - European heart journal, 1997 - academic.oup.com
The endothelium mediates a number of responses (relaxation or contraction) of arteries and
veins from animals and humans. The endothelium-dependent relaxations are due to the …

Cellular signaling and NO production

T Michel, PM Vanhoutte - Pflügers archiv-European journal of physiology, 2010 - Springer
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium-derived …

Endothelium‐mediated control of vascular tone: COX‐1 and COX‐2 products

M Félétou, Y Huang… - British journal of …, 2011 - Wiley Online Library
Endothelium‐dependent contractions contribute to endothelial dysfunction in various animal
models of aging, diabetes and cardiovascular diseases. In the spontaneously hypertensive …

Endothelium‐dependent contractions and endothelial dysfunction in human hypertension

D Versari, E Daghini, A Virdis… - British journal of …, 2009 - Wiley Online Library
The endothelium is a crucial regulator of vascular physiology, producing in healthy
conditions several substances with a potent antiatherosclerotic properties. Accordingly, the …

Endothelial dysfunction and aging: an update

MD Herrera, C Mingorance… - Ageing research …, 2010 - Elsevier
Aging is an important risk factor for the development of many cardiovascular diseases as
atherosclerosis and hypertension with a common underlying circumstance: the progressive …

Atherosclerosis-associated endothelial dysfunction

V Schächinger, AM Zeiher - Zeitschrift für Kardiologie, 2000 - Springer
The endothelium plays a crucial role in the process of atherosclerotic disease by its
regulatory functions on the vasculature, such as control of vasomotor tone, local hemostasis …

Mechanisms of endothelial dysfunction: clinical significance and preventive non-pharmacological therapeutic strategies

S Taddei, L Ghiadoni, A Virdis… - Current …, 2003 - ingentaconnect.com
Endothelium-derived NO is not only a potent vasodilator but also inhibits platelet
aggregation, vascular smooth muscle cell migration and proliferation, monocyte adhesion …