Economic impact of next-generation sequencing versus single-gene testing to detect genomic alterations in metastatic non–small-cell lung cancer using a decision …

NA Pennell, A Mutebi, ZY Zhou, ML Ricculli… - JCO Precision …, 2019 - ascopubs.org
PURPOSE The aim of the current study was to assess the economic impact of using next-
generation sequencing (NGS) versus single-gene testing strategies among patients with …

Total cost of testing for genomic alterations associated with next-generation sequencing versus polymerase chain reaction testing strategies among patients with …

J Vanderpoel, AL Stevens, B Emond… - Journal of Medical …, 2022 - Taylor & Francis
Background To assess the total cost of testing associated with next-generation sequencing
(NGS) versus polymerase chain reaction (PCR) testing strategies among patients with …

[HTML][HTML] Diagnostic value and cost-effectiveness of next-generation sequencing–based testing for treatment of patients with advanced/metastatic non-squamous non …

D Zou, W Ye, LM Hess, NR Bhandari, A Ale-Ali… - The Journal of Molecular …, 2022 - Elsevier
The study evaluated the diagnostic value and cost-effectiveness of next-generation
sequencing (NGS)–based testing versus various combinations of single-gene tests (SGTs) …

Cost effectiveness of multigene panel sequencing for patients with advanced non–small-cell lung cancer

L Steuten, B Goulart, NJ Meropol… - JCO Clinical Cancer …, 2019 - ascopubs.org
PURPOSE Compared with single-marker genetic testing (SMGT), multigene panel
sequencing (MGPS) has the potential to identify more patients with cancer who could benefit …

Comprehensive genomic profiling facilitates implementation of the national comprehensive cancer network guidelines for lung cancer biomarker testing and identifies …

JH Suh, A Johnson, L Albacker, K Wang… - The …, 2016 - academic.oup.com
Abstract Background. The National Comprehensive Cancer Network (NCCN) guidelines for
patients with metastatic non-small cell lung cancer (NSCLC) recommend testing for EGFR …

Association between availability of molecular genotyping results and overall survival in patients with advanced nonsquamous non–small-cell lung cancer

C Aggarwal, ME Marmarelis, WT Hwang… - JCO precision …, 2023 - ascopubs.org
PURPOSE Current guidelines recommend molecular genotyping for patients newly
diagnosed with metastatic nonsquamous (mNSq) non–small-cell lung cancer (NSCLC). The …

Clinical implications of plasma-based genotyping with the delivery of personalized therapy in metastatic non–small cell lung cancer

C Aggarwal, JC Thompson, TA Black, SI Katz… - JAMA …, 2019 - jamanetwork.com
Importance The clinical implications of adding plasma-based circulating tumor DNA next-
generation sequencing (NGS) to tissue NGS for targetable mutation detection in non–small …

Practice-level variation in molecular testing and use of targeted therapy for patients with non–small cell lung cancer and colorectal cancer

TJ Roberts, KL Kehl, GA Brooks, L Sholl… - JAMA Network …, 2023 - jamanetwork.com
Importance All patients with newly diagnosed non–small cell lung cancer (NSCLC) and
colorectal cancer (CRC) should receive molecular testing to identify those who can benefit …

Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and …

AC Tan, GGY Lai, G San Tan, SY Poon, B Doble… - Lung Cancer, 2020 - Elsevier
Objectives There is an expanding list of therapeutically relevant biomarkers for non-small
cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition …

[HTML][HTML] Biomarker testing and tissue journey among patients with metastatic non-small cell lung cancer receiving first-line therapy in The US Oncology Network

NJ Robert, JL Espirito, L Chen, E Nwokeji, M Karhade… - Lung Cancer, 2022 - Elsevier
Abstract Objectives The MYLUNG (Molecularly Informed Lung Cancer Treatment in a
Community Cancer Network) consortium pragmatic study assessed real-world biomarker …