A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates
MG Joyce, HAD King, I Elakhal-Naouar… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
stresses the continued need for next-generation vaccines that confer broad protection …
stresses the continued need for next-generation vaccines that confer broad protection …
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
MG Joyce, WH Chen, RS Sankhala, A Hajduczki… - Cell reports, 2021 - cell.com
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
HAD King, MG Joyce, I Lakhal-Naouar… - Proceedings of the …, 2021 - National Acad Sciences
Emergence of novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable …
CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable …
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge
KMG Wuertz, EK Barkei, WH Chen, EJ Martinez… - npj Vaccines, 2021 - nature.com
The emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of
vaccine protection. We evaluated whether a SARS-CoV-2 spike ferritin nanoparticle vaccine …
vaccine protection. We evaluated whether a SARS-CoV-2 spike ferritin nanoparticle vaccine …
SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses
The emergence of variants of concern, some with reduced susceptibility to COVID-19
vaccines underscores consideration for the understanding of vaccine design that optimizes …
vaccines underscores consideration for the understanding of vaccine design that optimizes …
Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques
RS Sankhala, KG Lal, JL Jensen, V Dussupt… - Nature …, 2024 - nature.com
The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased
susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation …
susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation …
[HTML][HTML] Nanoparticle vaccines based on the receptor binding domain (RBD) and heptad repeat (HR) of SARS-CoV-2 elicit robust protective immune responses
Various vaccine strategies have been proposed in response to the global COVID-19
pandemic, each with unique strategies for eliciting immune responses. Here, we developed …
pandemic, each with unique strategies for eliciting immune responses. Here, we developed …
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need
remains for a globally available vaccine that provides longer-lasting immunity against …
remains for a globally available vaccine that provides longer-lasting immunity against …
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
PJM Brouwer, M Brinkkemper, P Maisonnasse… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …
A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice
The development of a safe and effective SARS-CoV-2 vaccine is a public health priority. We
designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying …
designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying …