Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy

D Benvenuto, S Angeletti, M Giovanetti, M Bianchi… - Journal of Infection, 2020 - Elsevier
Background SARS-CoV-2 is a new coronavirus that has spread globally, infecting more than
150000 people, and being declared pandemic by the WHO. We provide here bio-informatic …

[HTML][HTML] Mutational frequencies of SARS-CoV-2 genome during the beginning months of the outbreak in USA

N Kaushal, Y Gupta, M Goyal, SF Khaiboullina… - Pathogens, 2020 - mdpi.com
SARS-CoV-2 has spread very quickly from its first reported case on 19 January 2020 in the
United Stated of America, leading WHO to declare pandemic by 11 March 2020. RNA …

[HTML][HTML] Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1

F Benedetti, GA Snyder, M Giovanetti… - Journal of Translational …, 2020 - Springer
Abstract Background The new Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-
CoV-2), which was first detected in Wuhan (China) in December of 2019 is responsible for …

Emergence of genomic diversity and recurrent mutations in SARS-CoV-2

L Van Dorp, M Acman, D Richard, LP Shaw… - Infection, Genetics and …, 2020 - Elsevier
SARS-CoV-2 is a SARS-like coronavirus of likely zoonotic origin first identified in December
2019 in Wuhan, the capital of China's Hubei province. The virus has since spread globally …

Decoding asymptomatic COVID-19 infection and transmission

R Wang, J Chen, Y Hozumi, C Yin… - The journal of physical …, 2020 - ACS Publications
One of the major challenges in controlling the coronavirus disease 2019 (COVID-19)
outbreak is its asymptomatic transmission. The pathogenicity and virulence of asymptomatic …

COVID‐2019: the role of the nsp2 and nsp3 in its pathogenesis

S Angeletti, D Benvenuto, M Bianchi… - Journal of medical …, 2020 - Wiley Online Library
Last December 2019, a new virus, named novel Coronavirus (COVID‐2019) causing many
cases of severe pneumonia was reported in Wuhan, China. The virus knowledge is limited …

Global SNP analysis of 11,183 SARS‐CoV‐2 strains reveals high genetic diversity

F Yuan, L Wang, Y Fang, L Wang - … and emerging diseases, 2021 - Wiley Online Library
Since first identified in December of 2019, COVID‐19 has been quickly spreading to the
world in few months and COVID‐19 cases are still undergoing rapid surge in most countries …

[HTML][HTML] Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function

A Berrio, V Gartner, GA Wray - PeerJ, 2020 - peerj.com
Background The emergence of a novel coronavirus (SARS-CoV-2) associated with severe
acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis …

[HTML][HTML] Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus)

TT Nguyen, PN Pathirana, T Nguyen, QVH Nguyen… - Scientific Reports, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly pathogenic
virus that has caused the global COVID-19 pandemic. Tracing the evolution and …

[HTML][HTML] The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage

X Lin, Z Sha, J Trimpert, D Kunec, C Jiang, Y Xiong… - Cell Host & Microbe, 2023 - cell.com
The historically dominant SARS-CoV-2 Delta variant and the currently dominant Omicron
variants carry a T492I substitution within the non-structural protein 4 (NSP4). Based on in …