Podoplanin associates with CD44 to promote directional cell migration

E Martín-Villar, B Fernández-Munoz… - Molecular biology of …, 2010 - Am Soc Cell Biol
Podoplanin is a transmembrane glycoprotein up-regulated in different human tumors,
especially those derived from squamous stratified epithelia (SCCs). Its expression in tumor …

[HTML][HTML] Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin

LN Cueni, I Hegyi, JW Shin, A Albinger-Hegyi… - The American journal of …, 2010 - Elsevier
The membrane glycoprotein podoplanin is expressed by several types of human cancers
and might be associated with their malignant progression. Its exact biological function and …

Podoplanin: a novel regulator of tumor invasion and metastasis

Q Dang, J Liu, J Li, Y Sun - Medical oncology, 2014 - Springer
Podoplanin, a small mucin-type sialoglycoprotein, was recently shown to be involved in
tumor progression. Podoplanin is overexpressed in cancer cells of various human …

[HTML][HTML] The potential role of podoplanin in tumour invasion

A Wicki, G Christofori - British journal of cancer, 2007 - nature.com
Podoplanin is a small mucin-like transmembrane protein, widely expressed in various
specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin …

[HTML][HTML] Inflammatory cytokines induce podoplanin expression at the tumor invasive front

A Kunita, V Baeriswyl, C Meda, E Cabuy… - The American journal of …, 2018 - Elsevier
Tumor invasion is a critical first step in the organismic dissemination of cancer cells and the
formation of metastasis in distant organs, the most important prognostic factor and the actual …

[HTML][HTML] Roles of podoplanin in malignant progression of tumor

H Suzuki, MK Kaneko, Y Kato - Cells, 2022 - mdpi.com
Podoplanin (PDPN) is a cell-surface mucin-like glycoprotein that plays a critical role in tumor
development and normal development of the lung, kidney, and lymphatic vascular systems …

[HTML][HTML] Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton

A Wicki, F Lehembre, N Wick, B Hantusch, D Kerjaschki… - Cancer cell, 2006 - cell.com
The expression of podoplanin, a small mucin-like protein, is upregulated in the invasive front
of a number of human carcinomas. We have investigated podoplanin function in cultured …

Expression of podoplanin in the invasion front of oral squamous cell carcinoma is not prognostic for survival

JC de Vicente, TR Santamarta, JP Rodrigo… - Virchows Archiv, 2015 - Springer
Podoplanin is involved in actin remodeling of the cytoskeleton of tumor cells and may
promote tumor cell invasion by increasing cell motility and formation of filopodia-like …

Podoplanin expression in basal and myoepithelial cells: utility and potential pitfalls

WA Kanner, MT Galgano, KA Atkins - … & Molecular Morphology, 2010 - journals.lww.com
Abstract Podoplanin, D2-40, is often used for highlighting lymphatics. However, it has been
described in a variety of normal and neoplastic tissues. We evaluated the expression of D2 …

Podoplanin: an emerging cancer biomarker and therapeutic target

H Krishnan, J Rayes, T Miyashita, G Ishii… - Cancer …, 2018 - Wiley Online Library
Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on
transformed cells, cancer associated fibroblasts and inflammatory macrophages that …