To understand the molecular actions of status epilepticus at the chromatin level, we studied
the effects of kainate‐induced status epilepticus on two different histone modifications at …

The Arabidopsis GCN5, ADA2a and ADA2b proteins are homologs of components of
several yeast and animal transcriptional coactivator complexes. Previous work has …

Recent years have seen major advances in elucidating the complexity of chromatin and its
role as an epigenetic regulator of gene expression in eukaryotes. We now have a basic …

A significant body of evidence has been accumulated that demonstrates decisive roles of
members of the Myc/Max/Mad network in the control of various aspects of cell behavior …

The SWI/SNF and SAGA chromatin-modifying complexes contain bromodomains that help
anchor these complexes to acetylated promoter nucleosomes. To study the importance of …

Uncontrolled generation of nitric oxide (NO) by inducible nitric-oxide synthase (iNOS) can
cause damage to host cells and inflammation, two undesirable events for virus spreading …

Neural stem cells and neurogenesis persist in the adult mammalian brain subventricular
zone (SVZ). Cells born in the rodent SVZ migrate to the olfactory bulb (Ob) where they …

The term “epigenetics” is defined as “heritable changes in gene expression that occur
without changes in DNA sequence”. Recently, it has been revealed that DNA methylation …

Cellular chromatin forms a dynamic structure that maintains the stability and accessibility of
the host DNA genome. Viruses that enter and persist in the nucleus must, therefore, contend …

DNA processes, including transcriptional activation, are largely governed by histone
modifications. For most eukaryotes, chromatin-remodeling machines have been identified …