Translational Control Mechanisms Analyzed in Neurospora crassa

J Wei - 2013 - oaktrust.library.tamu.edu
The Neurospora crassa arg-2 gene encodes the small subunit of carbamoyl phosphate
synthetase, the first enzyme in fungal arginine (Arg) biosynthesis. The arginine attenuator …

Translation initiation from conserved non-AUG codons provides additional layers of regulation and coding capacity

IP Ivanov, J Wei, SZ Caster, KM Smith, AM Michel… - MBio, 2017 - Am Soc Microbiol
Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying
transcription activators that drive the transcriptional response to amino acid limitation. The …

[图书][B] The evolutionarily conserved arginine attenuator peptide regulates the movement of ribosomes that have translated it

Z Wang - 2000 - search.proquest.com
The major focus of this study is to elucidate the mechanism of translational control of arg-2.
arg-2 is a gene involved in Neurospora crassa arginine (Arg) biosynthesis, and translation of …

Evolutionarily conserved features of the arginine attenuator peptide provide the necessary requirements for its function in translational regulation

P Fang, Z Wang, MS Sachs - Journal of Biological Chemistry, 2000 - ASBMB
Neurospora crassa arg-2 mRNA contains an evolutionarily conserved upstream open
reading frame (uORF) encoding the Arg attenuator peptide (AAP) that confers negative …

[PDF][PDF] Arginine-specific negative regulation of Neurospora crassa arg-2 mediated by the arg-2 uORF and Arginine

JM Carroll - 1997 - digitalcollections.ohsu.edu
Neurosporacrassaarg-2 encodesthe small subunitof Arg-specificcarbamoyl phosphate
synthetase and is negatively regulated by arginine. This regulation is mediated by a 24 …

[图书][B] Analyses of the fungal arginine attenuator peptide's role in the regulation of ribosome stalling

P Fang - 2003 - search.proquest.com
The arginine attenuator peptides (AAP), specified by an evolutionarily conserved upstream
open reading frame (uORF) in mRNAs specifying small subunit of carbamoyl phosphate …

A highly conserved mechanism of regulated ribosome stalling mediated by fungal arginine attenuator peptides that appears independent of the charging status of …

Z Wang, A Gaba, MS Sachs - Journal of Biological Chemistry, 1999 - ASBMB
The Arg attenuator peptide (AAP) is an evolutionarily conserved peptide involved in Arg-
specific negative translational control. It is encoded as an upstream open reading frame …

Translational regulation in response to changes in amino acid availability in Neurospora crassa

Z Luo, M Freitag, MS Sachs - Molecular and cellular biology, 1995 - Am Soc Microbiol
We examined the regulation of Neurospora crassa arg-2 and cpc-1 in response to amino
acid availability. arg-2 encodes the small subunit of arginine-specific carbamoyl phosphate …

The evolutionarily conserved eukaryotic arginine attenuator peptide regulates the movement of ribosomes that have translated it

Z Wang, P Fang, MS Sachs - Molecular and cellular biology, 1998 - Taylor & Francis
Translation of the upstream open reading frame (uORF) in the 5′ leader segment of the
Neurospora crassa arg-2 mRNA causes reduced initiation at a downstream start codon …

A UV-induced mutation in Neurospora that affects translational regulation in response to arginine

M Freitag, N Dighde, MS Sachs - Genetics, 1996 - academic.oup.com
The Neurospora crmsu arg-2 gene encodes the small subunit of arginine-specific carbamoyl
phosphate synthetase. The levels of arg-2 mRNA and mRNA translation are negatively …