PPARs are mediators of anti-cancer properties of superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with conjugated linoleic acid

M Ricci, M Miola, C Multari, E Borroni… - Chemico-Biological …, 2018 - Elsevier
Breast cancer chemotherapy can cause side effects due to nonspecific drug delivery, low
solubility and fast metabolism of drugs used in conventional therapy. Moreover, the …

Innovative superparamagnetic iron-oxide nanoparticles coated with silica and conjugated with linoleic acid: Effect on tumor cell growth and viability

G Muzio, M Miola, S Ferraris, M Maggiora… - Materials Science and …, 2017 - Elsevier
One of the goals for the development of more effective cancer therapies with reduced toxic
side effects is the optimization of innovative treatments to selectively kill tumor cells. The use …

Therapeutic Potential of Methotrexate-Loaded Superparamagnetic Iron Oxide Nanoparticles Coated with Poly(lactic-co-glycolic acid) and Polyethylene Glycol against …

S Bhattacharya, BG Prajapati, N Ali, M Mohany… - ACS …, 2023 - ACS Publications
Novel superparamagnetic iron oxide nanoparticles (SPIONs) of Methotrexate (MTX) were
developed using supercritical liquid technology and optimized with a Box–Behnken design …

[HTML][HTML] Blocking interleukin-4 receptor α using polyethylene glycol functionalized superparamagnetic iron oxide nanocarriers to inhibit breast cancer cell proliferation

AP Shaik, AS Shaik, A Al Majwal… - Cancer Res …, 2017 - synapse.koreamed.org
Purpose The specific targeting of interleukin-4 receptor α (IL4Rα) receptor offers a promising
therapeutic approach for inhibition of tumor cell progression in breast cancer patients. In the …

Doxorubicin-loaded iron oxide nanoparticles induce oxidative stress and cell cycle arrest in breast cancer cells

EP Hernandes, D Lazarin-Bidóia, RD Bini… - Antioxidants, 2023 - mdpi.com
Cancer is one of the most common diseases nowadays and derives from the uncontrollable
growth of a single cell. Magnetic nanoparticles (NpMag) offer various possibilities for use in …

Differential effect of polyvinylpyrrolidone-coated superparamagnetic iron oxide nanoparticles on BT-474 human breast cancer cell viability

M Aliakbari, E Mohammadian, A Esmaeili… - Toxicology in Vitro, 2019 - Elsevier
Polyvinylpyrrolidone superparamagnetic iron oxide nanoparticles (PVP-SPIONs) have
unique properties. Due to these characteristics, PVP-SPIONs have been used in several …

Cytotoxicity of methotrexate conjugated to glycerol phosphate modified superparamagnetic iron oxide nanoparticles

DK Deda, RM Cardoso, RK Kawassaki… - … of Nanoscience and …, 2021 - ingentaconnect.com
A systematic study was carried out to evaluate the uptake and cytotoxicity of methotrexate
(MTX) conjugated to superparamagnetic iron oxide nanoparticles (SPIONs) modified with …

Iron oxide nanoparticles for breast cancer theranostics

MS Shakil, MA Hasan, SR Sarker - Current drug metabolism, 2019 - ingentaconnect.com
Background: Breast cancer is the second leading cause of death in women worldwide. The
extremely fast rate of metastasis and ability to develop resistance mechanism to all the …

Genotoxicity and biocompatibility of superparamagnetic iron oxide nanoparticles: Influence of surface modification on biodistribution, retention, DNA damage and …

S Ghosh, I Ghosh, M Chakrabarti… - Food and Chemical …, 2020 - Elsevier
Superparamagnetic iron oxide nanoparticles (SPION) require stable surface modifications to
render safe nanocapsules for biomedical applications. Herein, two types of surface modified …

Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake

JM Poller, J Zaloga, E Schreiber… - International journal …, 2017 - Taylor & Francis
Superparamagnetic iron oxide nanoparticles (SPIONs) are promising tools for the treatment
of different diseases. Their magnetic properties enable therapies involving magnetic drug …