Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …

Innate and adaptive immunity are the major defence mechanisms of higher organisms
against inherent and environmental threats. Innate immunity is present already in unicellular …

Inflamm-aging, that is the age-associated inflammatory status, is considered one of the most
striking consequences of immunosenescence, as it is believed to be linked to the majority of …

Circulating microRNAs (miRs) have been investigated as diagnostic/prognostic biomarkers
in human diseases. However, little is known about their expression throughout the aging …

Background: The aging phenotype in humans is very heterogeneous and can be described
as a complex mosaic resulting from the interaction of a variety of environmental, stochastic …

At present, individuals can live up to 80–120 years, a time much longer than that of our
ancestors, as a consequence of the improvements in life conditions and medical care. Thus …

Nowadays, people are living much longer than they used to do, however they are not free
from ageing. Ageing, an inexorable intrinsic process that affects all cells, tissues, organs and …

The intestinal bacterial ecosystem has gained increasing interest from the scientific
community because of its demonstrated involvement in the aetiology and/or outcome of …

Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also
expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation …