An overview on mRNA-based vaccines to prevent monkeypox infection
M Natami, A Gorgzadeh, A Gholipour… - Journal of …, 2024 - Springer
The human monkeypox virus (Mpox) is classified as a member of the Poxviridae family and
belongs to the Orthopoxvirus genus. Mpox possesses double-stranded DNA, and there are …
belongs to the Orthopoxvirus genus. Mpox possesses double-stranded DNA, and there are …
Mpox: An Overview of Pathogenesis, Diagnosis, and Public Health Implications
F Branda, C Romano, M Ciccozzi, M Giovanetti… - Journal of Clinical …, 2024 - mdpi.com
Mpox, caused by viruses of the genus Orthopoxvirus, is an emerging threat to human and
animal health. With increasing urbanization and more frequent interaction between humans …
animal health. With increasing urbanization and more frequent interaction between humans …
Immunogenicity and efficacy of TNX-1800, A live virus recombinant poxvirus vaccine candidate, against SARS-CoV-2 challenge in nonhuman primates
M Awasthi, A Macaluso, D Myscofski, J Prigge, F Koide… - Vaccines, 2023 - mdpi.com
TNX-1800 is a synthetically derived live recombinant chimeric horsepox virus (rcHPXV)
vaccine candidate expressing Wuhan SARS-CoV-2 spike (S) protein. The primary objective …
vaccine candidate expressing Wuhan SARS-CoV-2 spike (S) protein. The primary objective …
Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus
T Ye, J Zhou, C Guo, K Zhang, Y Wang, Y Liu, J Zhou… - Cell Reports, 2024 - cell.com
The 2022 mpox outbreak led the World Health Organization (WHO) to declare it a public
health emergency of international concern (PHEIC). There is a need to develop more …
health emergency of international concern (PHEIC). There is a need to develop more …
Immunogenicity and tolerability of a SARS-CoV-2 TNX-1800, a live recombinant poxvirus vaccine candidate, in Syrian Hamsters and New Zealand White Rabbits
TNX-1800 is a preclinical stage synthetic-derived live attenuated chimeric horsepox virus
vaccine engineered to express the SARS-CoV-2 spike (S) gene. The objectives of this study …
vaccine engineered to express the SARS-CoV-2 spike (S) gene. The objectives of this study …
Vaccinia virus tiantan strain is inefficient in eliciting cross-reactive immunity against the emerging monkeypox virus strain
L Tian, Y Zhang, Q Liu, L Ruan, F Ren… - Emerging microbes & …, 2024 - Taylor & Francis
Dear Editor, Orthopoxviruses (OPXVs) are a genus of large DNA virus that are responsible
for some of the most virulent diseases of humans and animals, including variola virus …
for some of the most virulent diseases of humans and animals, including variola virus …
Circular RNA vaccines against monkeypox virus provide potent protection against vaccinia virus infection in mice
J Zhou, T Ye, Y Yang, E Li, K Zhang, Y Wang, S Chen… - Molecular Therapy, 2024 - cell.com
Since the outbreak of monkeypox (mpox) in 2022, widespread concern has been placed on
imposing an urgent demand for specific vaccines that offer safer and more effective …
imposing an urgent demand for specific vaccines that offer safer and more effective …
Clinical features and viral load variations of Mpox: a retrospective study in Chongqing, China
S Yang, C Xia, Y Zhang, Y Shen, C Xia, Y Lu… - BMC Infectious …, 2024 - Springer
Abstract Purpose Since May 2022, Mpox has spread extensively outside of Africa, posing a
serious threat to the health of people globally, and particularly to the men who have sex with …
serious threat to the health of people globally, and particularly to the men who have sex with …
Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities
Background The 2022-2023 global mpox outbreak primarily affected gay, bisexual, and
other men who have sex with men (GBM). It was met with swift community and public health …
other men who have sex with men (GBM). It was met with swift community and public health …
[PDF][PDF] Review of virological methods for laboratory diagnosis and characterization of monkeypox virus (MPXV): lessons learned from the 2022 Mpox outbreak
KR Rus, S Zakotnik, M Sagadin… - Acta …, 2024 - acta-apa.mf.uni-lj.si
Monkeypox virus (MPXV), originally endemic in West Africa (Clade II) and Central Africa
(Clade I), has recently emerged worldwide and has reinforced the need for rapid and …
(Clade I), has recently emerged worldwide and has reinforced the need for rapid and …