Geroscience puts mechanisms of aging as a driver of the most common age-related
diseases and dysfunctions. Under this perspective, addressing the basic mechanisms of …

Inflammaging refers to the age-related low grade, sterile, chronic, systemic, and long-lasting
subclinical, proinflammatory status, currently recognized as the main risk factor for …

Background Sex differences play a critical role in the incidence and severity of
cardiovascular diseases, whereby men are at a higher risk of developing cardiovascular …

Senescence is a complex cell state characterized by stable cell cycle arrest and a unique
secretory pattern known as the senescence-associated secretory phenotype (SASP). The …

In the event of a radiological or nuclear accident, or when physical dosimetry is not
available, the scoring of radiation-induced chromosomal aberrations in lymphocytes …

Women acquire HIV through sexual transmission, with increasing incidence in women> 50
years old. Identifying protective mechanisms in the female genital tract (FGT) is important to …

The prevalence of periodontitis is increasing with the aging of the global population.
Periodontitis has been suggested to accelerate aging and increase mortality. The present …

Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

Background Cellular senescence has been regarded as a therapeutic target for ageing and
age-related diseases. Several senotherapeutic agents have been proposed, including …

Mesenchymal stem/stromal cells (MSCs) are a promising therapeutic tool in cell therapy and
tissue engineering because of their multi-lineage differentiation capacity …