Corona Virus Disease 2019 (COVID-19) continues to be a burden for human health since its
outbreak in Wuhan, China in December 2019. Recently, the emergence of new variants of …

Objective This study evaluated the clinical efficacy and safety of interleukin-1 (IL-1) blockade
for patients with COVID-19. Methods The PubMed, Web of Science, Ovid Medline, Embase …

COVID-19-associated intensive care unit (ICU) admissions were recognized as critical
health issues that contributed to morbidity and mortality in SARS-CoV-2-infected patients …

Abstract SARS‐CoV‐2 triggers inflammasome‐dependent release of pro‐inflammatory
cytokine IL‐1β and pyroptosis, therefore, contributes to the huge inflammatory response …

Ethnopharmacological relevance Yunvjian decoction (YNJ) is a traditional Chinese herbal
prescription that has been used in the clinical treatment of periodontitis. However, the …

The structure proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
such as nucleocapsid protein (N protein) and envelop protein (E protein), are considered to …

Introduction In the present study, the impact of BromAc®, a specific combination of
bromelain and acetylcysteine, on the SARS-CoV-2-specific inflammatory response was …

Gasdermins are effectors of pyroptosis downstream of diverse signaling pathways.
Emerging evidence suggests that a number of post-translational modifications regulate the …

Abstract Background Extracellular vesicles (EVs), containing microRNAs (miRNAs) and
other molecules, play a central role in intercellular communication, especially in viral …

Pregnancy is characterized by a delicate immune balance; therefore, infectious diseases
might increase the risk of adverse pregnancy outcomes (APOs). Here, we hypothesize that …