One-carbon metabolism (OCM) is a network of biochemical reactions delivering one-carbon
units to various biosynthetic pathways. The folate cycle and methionine cycle are the two key …

Insight on the underlying mechanisms of aging will advance our ability to extend healthspan,
treat age-related pathology and improve quality of life. Multiple genetic and pharmacological …

Fully understanding the environmental implications of engineered nanomaterials is crucial
for their safe and sustainable use. Cyanobacteria, as the pioneers of the planet earth, play …

The human population is aging, and the need for interventions to slow progression of age-
related diseases (geroprotective interventions) is growing. Repurposing compounds already …

Folate receptor (FR) alpha (FOLR1) and beta (FOLR2) are membrane-anchored folate
transporters that are expressed at low levels in normal tissues, while their expression is …

This review delves into the intricate relationship between excess folate (vitamin B9) intake,
especially its synthetic form, namely, folic acid, and its implications on health and disease …

Hexagonal boron nitride (h-BN) nanomaterials have attracted numerous attentions for
application in various fields, including environmental governance. Understanding the …

One of the challenges facing science/biology today is uncovering the molecular bases that
support and determine animal and human longevity. Nature, in offering a diversity of animal …

Neoplasias pose a significant threat to aging society, underscoring the urgent need to
overcome the limitations of traditional chemotherapy through pioneering strategies …

ATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein,
carbohydrate, and lipid metabolism. The physiological consequences as well as the …