Making Sense of the Costs of Adversity Throughout the Lifespan on Aging in Humans and Other Animals

R Sapolsky, A Bartolomucci - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Social adversity, particularly early in life, can cause lifelong damage to health; by now,
numerous studies examine this relationship in non-human species, producing some …

Chronic social and psychological stress impact select neuropathologies in the PS19 mouse model of tauopathy

CE Lyons, SI Graves, M Razzoli… - Psychosomatic …, 2023 - journals.lww.com
Objective Despite advances toward understanding the etiology of Alzheimer's disease (AD),
it remains unclear which aspects of this disease are affected by environmental factors …

The energetics of cellular life transitions

AS Monzel, M Levin, M Picard - Life metabolism, 2024 - academic.oup.com
Major life transitions are always difficult because change costs energy. Recent findings have
demonstrated how mitochondrial oxidative phosphorylation (OxPhos) defects increase the …

The fortunes and misfortunes of social life across the life course: a new era of research from field, laboratory and comparative studies

A Bartolomucci, J Tung, KM Harris - Neuroscience & Biobehavioral …, 2024 - Elsevier
Social gradients in health and aging have been reported in studies across many human
populations, and-as the papers included in this special collection highlight–also occur …

Reflections on resilience

E Chen, T Jiang, MA Chen, GE Miller - Development and …, 2024 - cambridge.org
Resilience research has long sought to understand how factors at the child, family, school,
community, and societal levels shape adaptation in the face of adversities such as poverty …

[HTML][HTML] Childhood maltreatment and biological aging in middle adulthood: The role of psychiatric symptoms

CS Widom, HH Do, QC Miller, M Javakhisvili… - … Psychiatry Global Open …, 2024 - Elsevier
Background Childhood maltreatment and psychiatric morbidity have each been associated
with accelerated biological aging primarily through cross-sectional studies. Using data from …

[HTML][HTML] Associations of Systemic Inflammation and Senescent Cell Biomarkers with Clinical Outcomes in Older Adults with Schizophrenia

MKK Chui, K Schneider, K Miclau, SC LaHue… - medRxiv, 2024 - ncbi.nlm.nih.gov
Individuals with schizophrenia suffer from higher morbidity and mortality throughout life
partly due to acceleration of aging-related diseases and conditions. Systemic inflammation …

Stress-relief, meditation, and their pervasive influence on health and anti-aging: a holistic perspective

B Doskaliuk - Anti-Aging Eastern Europe, 2023 - antiagingeeu.com
This article explores the intricate connection between stress, aging, and meditation. Chronic
stress accelerates physical and cognitive aging. Meditation emerges as a potent tool by …

Neurobiology of Social Stress and Age-related Neurodegeneration

J Wang, SJ Russo - Neuroscience and biobehavioral …, 2023 - pubmed.ncbi.nlm.nih.gov
Neurobiology of Social Stress and Age-related Neurodegeneration Neurobiology of Social
Stress and Age-related Neurodegeneration Neurosci Biobehav Rev. 2023 Nov 24:105482. doi …

[PDF][PDF] The somato-cognitive energy conservation theory of aging

Aging involves seemingly paradoxical changes in cellular and whole-body energy
metabolism. Senescence activates costly molecular processes that increase cellular energy …