[HTML][HTML] Interconnections between inflammageing and immunosenescence during ageing

T Teissier, E Boulanger, LS Cox - Cells, 2022 - mdpi.com
Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

AGE/RAGE in diabetic kidney disease and ageing kidney

XQ Wu, DD Zhang, YN Wang, YQ Tan, XY Yu… - Free Radical Biology …, 2021 - Elsevier
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …

[HTML][HTML] Advanced glycation end products and diabetes mellitus: mechanisms and perspectives

M Khalid, G Petroianu, A Adem - Biomolecules, 2022 - mdpi.com
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …

[HTML][HTML] Advanced glycation end products and their effect on vascular complications in type 2 diabetes mellitus

J Lee, JS Yun, SH Ko - Nutrients, 2022 - mdpi.com
Diabetes is well established as a chronic disease with a high health burden due to mortality
or morbidity from the final outcomes of vascular complications. An increased duration of …

IDF Diabetes Atlas: Diabetes and oral health–A two-way relationship of clinical importance

WS Borgnakke - Diabetes research and clinical practice, 2019 - Elsevier
The current scientific evidence for the bi-directional associations between oral health and
diabetes is summarized. The universal biologic mechanisms and demographic and …

[HTML][HTML] Targeting HMGB1: an available therapeutic strategy for breast cancer therapy

H Dong, L Zhang, S Liu - International journal of biological …, 2022 - ncbi.nlm.nih.gov
HMGB1 is a member of highly conserved high mobility group protein superfamily with
intracellular and extracellular distribution. Abnormal HMGB1 levels are frequently …

[HTML][HTML] The role of phosphatidylserine on the membrane in immunity and blood coagulation

J Wang, C Yu, J Zhuang, W Qi, J Jiang, X Liu… - Biomarker …, 2022 - Springer
The negatively charged aminophospholipid, phosphatidylserine (PtdSer), is located in the
inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer …

A novel role of Nano selenium and sildenafil on streptozotocin-induced diabetic nephropathy in rats by modulation of inflammatory, oxidative, and apoptotic pathways

MF El-Azab, AA Al-Karmalawy, SA Antar, PA Hanna… - Life sciences, 2022 - Elsevier
Aims The present study aimed to investigate the effect of nano selenium, sildenafil, and their
combination on inflammation, oxidative stress, and apoptosis in streptozotocin-induced …

Insulin/IGF axis and the Receptor for Advanced Glycation End Products: role in meta-inflammation and potential in cancer therapy

V Vella, R Lappano, E Bonavita, M Maggiolini… - Endocrine …, 2023 - academic.oup.com
In metabolic conditions such as obesity and diabetes, which are associated with
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …

Redoxisome and diabetic retinopathy: Pathophysiology and therapeutic interventions

I Sharma, KS Yadav, MN Mugale - Pharmacological Research, 2022 - Elsevier
Diabetic retinopathy (DR) is a chronic microvascular complication of diabetes mellitus (DM).
It is a worldwide growing epidemic disease considered to be the leading cause of vision …