The antiretroviral treatment (ART) developed to control HIV infection led to a revolution in the
prognosis of people living with HIV (PLWH). PLWH underwent from suffering severe disease …

Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) are pathogens
responsible for millions of new infections each year; together, they cause high morbidity and …

The advent of proteomics offers an unprecedented opportunity to predict dementia onset.
We examined this in data from 52,645 adults without dementia in the UK Biobank, with 1,417 …

Background DNA methylation-based estimators of biological age are reliable biomarkers of
the ageing process. We aimed to investigate a range of epigenetic ageing biomarkers in a …

People living with HIV face a high risk of mental illness, especially depression. We do not yet
know the precise neurobiological mechanisms underlying HIV-associated depression …

Defective HIV-1 proviruses represent a population of viral genomes that are selected for by
immune pressures, and clonally expanded to dominate the persistent HIV-1 proviral genome …

People with HIV (PWH) experience accentuated biological aging, as defined by markers of
inflammation, immune dysfunction, and the epigenetic clock. They also have an elevated …

Targeted metabolomics studies reported metabolic abnormalities in both treated and
untreated people living with human immunodeficiency virus (HIV)(PLHIV). The present study …

Although gut microbiota alteration and related blood microbe profiles in human
immunodeficiency virus (HIV)-infected individuals are associated with the disease …

People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …