Overindulgence, excessive consumption, and a pattern of compulsive use of natural
rewards, such as certain foods or drugs of abuse, may result in the development of obesity …

Alcohol abuse causes profound damage to both the developing brain and the adult brain.
Prenatal exposure to alcohol results in a wide range of deficits known as fetal alcohol …

Growing evidence points to a critical involvement of the extracellular matrix (ECM) in the
pathophysiology of schizophrenia (SZ). Decreases of perineuronal nets (PNNs) and altered …

Both early life aversive experiences and intrinsic alterations in early postnatal
neurodevelopment are considered predisposing factors for psychiatric disorders, such as …

Sleep quality varies widely across individuals, especially during normal aging, with impaired
sleep contributing to deficits in cognition and emotional regulation. Sleep can also be …

Introduction Transitions between sleep and waking and sleep-dependent cortical
oscillations are heavily dependent on GABAergic neurons. Importantly, GABAergic neurons …

Developmental exposure to ethanol is a leading cause of cognitive, emotional and
behavioral problems, with fetal alcohol spectrum disorder (FASD) affecting more than 1: 100 …

In animal models that mimic human third-trimester fetal development, ethanol causes
substantial cellular apoptosis in the brain, but for most brain structures, the extent of …

Prenatal alcohol exposure is the leading nongenetic cause of human intellectual
impairment. The long-term impacts of prenatal alcohol exposure on health and well-being …

Exposure to ethanol during the last trimester equivalent of human pregnancy causes
apoptotic neurodegeneration in the developing brain, an effect that is thought to be …