Adverse childhood experiences (ACE) are associated with HPA axis dysregulation at
younger ages, but there is scarcity of evidence for this association at older ages. To add to …

One of the proposed mechanisms linking childhood stressor exposure to negative mental
and physical health outcomes in later life is cellular aging. In this prospective, longitudinal …

In recent decades, pubertal onset in girls has been considered to occur at an earlier age
than previously. Exposure to endocrine-disrupting chemicals (EDCs) has been associated …

Childhood adversity is a common, powerful risk factor for future mental and physical health
problems. Appropriately aggregating and categorizing discrete adverse experiences into …

By affecting core neurobiological systems early in development, early life adversities (ELAs)
might confer latent vulnerability to future psychopathologies. This coordinate-based meta …

Purpose Early puberty is associated with adverse health outcomes over the life course, and
Black and Hispanic girls experience puberty earlier than girls of other racial/ethnic …

In adulthood, stress exposure and genetic risk heighten psychological vulnerability by
accelerating neurobiological senescence. To investigate whether molecular and brain …

Background A child's socioeconomic environment can shape central aspects of their life,
including vulnerability to mental disorders. Negative environmental influences in youth may …

Over the past 50 years, there has been a major shift in age distribution of patients with
congenital heart disease (CHD) thanks to significant advancements in medical and surgical …

Objective The processes facilitating resilience are likely to be influenced by individual,
familial and contextual factors that are dynamic across the life-course. These factors have …