Importance Childhood adversity (CA) is a powerful determinant of long-term physical and
mental health that is associated with elevated risk for chronic disease and psychopathology …

Highlights•Sensitive periods in humans are studied using methods developed in animal
models•Environmental deprivation is the predominant approach to studying sensitive …

Childhood adversity (CA) is associated with increased risk for physical and mental health
problems, with alterations in vagal regulation (an aspect of autonomic functioning indexed …

Abstract Purpose of Review Acceleration of biological processes of aging is hypothesized to
drive excess morbidity and mortality in socially disadvantaged populations. DNA methylation …

The links between early life stress (ELS) and the emergence of psychopathology such as
increased anxiety and depression are now well established, although the specific …

In a previous Perspectives article, we described conceptual problems that pose challenges
for research on the effects of childhood adversity and offered promising directions for future …

Children from low socioeconomic status (SES) backgrounds often have more negative self-
views than their peers. How are these self-views shaped by teacher–student interactions in …

Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …

Background Multiple published sources from around the world have confirmed an
association between an array of adverse childhood experiences (ACEs) and other traumatic …

Childhood maltreatment has been suggested to have an adverse impact on
neurodevelopment, including microstructural brain abnormalities. Existing neuroimaging …