Objective Exposure to adverse childhood experiences (ACEs) is linked to disruptions in
typical neurodevelopment of brain structures and functioning, including changes in …

People exposed to adverse childhood experiences (ACEs) suffer from an increased risk of
chronic disease and shorter lifespan. These individuals also tend to exhibit accelerated …

Exposure to adversity can accelerate biological aging. However, existing biomarkers of early
aging are either costly and difficult to collect, like epigenetic signatures, or cannot be …

Early life adversities (ELA), include experiences such as child maltreatment, household
dysfunction, bullying, exposure to crime, discrimination, bias, and victimization, and are …

Adversity, including abuse, neglect, and poverty, impacts child brain development. However,
the developing brain is highly plastic, and some of the impacts of childhood adversity may …

Sex is a significant source of heterogeneity in schizophrenia, with more negative symptoms
in males and more affective symptoms and internalizing comorbidity in females. In this …

Alterations in hypothalamic–pituitary–adrenal (HPA) axis and its effector hormone cortisol
have been proposed as one possible mechanism linking child maltreatment experiences to …

Depression is a chronic and debilitating condition that often emerges during adolescence, a
period of significant brain maturation. Few studies, however, have examined how …

Early pubertal timing has consistently been associated with internalizing psychopathology in
adolescent girls. Here, we aimed to examine whether the association between timing and …

Children's cognitive functioning and educational performance are socially stratified. Social
inequality, including classism and racism, may operate partly via epigenetic mechanisms …