Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Transforming growth factor-β (TGFβ) isoforms are upregulated and activated in myocardial
diseases and have an important role in cardiac repair and remodelling, regulating the …

Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic.
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …

Tissue fibrosis and organ dysfunction are hallmarks of age-related diseases including heart
failure, but it remains elusive whether there is a common pathway to induce both events …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Aging is an important risk factor for cardiovascular diseases, and aging‐related cardiac
dysfunction serves as a major determinant of morbidity and mortality in elderly populations …

The aging process is a complex biological phenomenon that results in the gradual decline of
physiological function and an increased risk of age-related diseases. While aging is a …

Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Abstract Purpose of Review The risk of cardiovascular complications due to SARS-CoV-2
are significantly increased within the first 6 months of the infection. Patients with COVID-19 …

As the global aging process continues to lengthen, aging-related diseases (eg, chronic
obstructive pulmonary disease (COPD), heart failure) continue to plague the elderly …