Biological age (BA) is important for clinical monitoring and preventing aging-related
disorders and disabilities. Clinical and/or cellular biomarkers are measured and integrated …

Biological clocks have been developed at different molecular levels and were found to be
more advanced in the presence of somatic illness and mental disorders. However, it is …

The world's population is ageing, and most older adults experience a later life burdened with
disease and disability. Frailty is a multidimensional and dynamic condition characterized by …

Plasma transfusions are standard treatments to replace missing proteins in people with rare
genetic diseases. Prior studies have demonstrated that heterochronic parabiosis has …

Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

All humans age, but how we age—and how fast—differs considerably from person to
person. This deviation between apparent age and chronological age is often referred to as …

Cytosine methylation patterns have not yet been thoroughly studied in horses. Here, we
profile n= 333 samples from 42 horse tissue types at loci that are highly conserved between …

Biological age captures a person's age-related risk of unfavorable outcomes using
biophysiological information. Multivariate biological age measures include frailty scores and …

The existence of a sex gap in human health and longevity has been widely documented.
Autosomal DNA methylation differences between males and females have been reported …

Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …