Echocardiographic heart ageing patterns predict cardiovascular and non-cardiovascular events and reflect biological age: the SardiNIA study

A Ganau, M Orrù, M Floris, PS Saba… - European Journal of …, 2024 - academic.oup.com
Aims Age is a crucial risk factor for cardiovascular (CV) and non-CV diseases. As people
age at different rates, the concept of biological age has been introduced as a personalized …

Recalibrating the epigenetic clock after exposure to trauma: The role of risk and protective psychosocial factors

D Mehta, D Bruenig, J Pierce… - Journal of psychiatric …, 2022 - Elsevier
Background Epigenetic aging is associated with a plethora of negative health outcomes and
increased mortality. Yet, the dynamicity of epigenetic age after exposure to trauma and the …

Whole blood metabolomics in aging research

H Kondoh, M Kameda, M Yanagida - International journal of molecular …, 2020 - mdpi.com
Diversity is observed in the wave of global aging because it is a complex biological process
exhibiting individual variability. To assess aging physiologically, markers for biological aging …

Linking brain age gap to mental and physical health in the Berlin aging study II

P Jawinski, S Markett, J Drewelies, S Düzel… - Frontiers in Aging …, 2022 - frontiersin.org
From a biological perspective, humans differ in the speed they age, and this may manifest in
both mental and physical health disparities. The discrepancy between an individual's …

[HTML][HTML] Leisure-time and occupational physical activity associates differently with epigenetic aging

A Kankaanpää, A Tolvanen, S Bollepalli… - … and Science in …, 2021 - ncbi.nlm.nih.gov
Purpose Greater leisure-time physical activity (LTPA) associates with healthier lives, but
knowledge regarding occupational physical activity (OPA) is more inconsistent. DNA …

Associations between life-course socioeconomic conditions and the pace of aging

S Schrempft, DW Belsky, B Draganski… - The Journals of …, 2022 - academic.oup.com
Background Socioeconomic disadvantage is a well-established predictor of morbidity and
mortality, and is thought to accelerate the aging process. This study examined associations …

Predictors of biological age: the implications for wellness and aging research

T Lohman, G Bains, L Berk… - … and Geriatric Medicine, 2021 - journals.sagepub.com
As healthspan and lifespan research breakthroughs have become more commonplace, the
need for valid, practical markers of biological age is becoming increasingly paramount. The …

Modeling biological age using blood biomarkers and physical measurements in Chinese adults

L Chen, Y Zhang, C Yu, Y Guo, D Sun, Y Pang, P Pei… - …, 2023 - thelancet.com
Background This study aimed to: 1) assess the associations of biological age acceleration
based on Klemera and Doubal's method (KDM-AA) with long-term risk of all-cause mortality; …

Patterns and life course determinants of Black–White disparities in biological age acceleration: A decomposition analysis

CE Boen, YC Yang, AE Aiello, AC Dennis… - …, 2023 - read.dukeupress.edu
Despite the prominence of the weathering hypothesis as a mechanism underlying racialized
inequities in morbidity and mortality, the life course social and economic determinants of …

Early life adversity predicts an accelerated cellular aging phenotype through early timing of puberty

EJ Hamlat, TB Neilands, B Laraia, J Zhang… - Psychological …, 2023 - cambridge.org
BackgroundThe current study examined if early adversity was associated with accelerated
biological aging, and if effects were mediated by the timing of puberty. MethodsIn early mid …