Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly
worldwide. However, the complexity of AD pathogenesis leads to discrepancies in the …

The world continues to contend with COVID-19, fueled by the emergence of viral variants. At
the same time, a subset of convalescent individuals continues to experience persistent and …

The mechanistic target of rapamycin (mTOR) signaling pathway plays a major role in key
cellular processes including metabolism and differentiation; however, the role of mTOR in …

Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Abstract Alzheimer's disease (AD), the most common form of dementia worldwide, is a mixed
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …

Modernization of society from a rural, hunter-gatherer setting into an urban and industrial
habitat, with the associated dietary changes, has led to an increased prevalence of …

Introduction: Stem cell-based regenerative medicine has provided an excellent opportunity
to investigate therapeutic strategies and innovative treatments for Alzheimer's disease (AD) …

Background Aerobic exercise (AE) may slow age-related cognitive decline. However, such
cognition-sparing effects are not uniform across cognitive domains and studies. Transcranial …

Background Population-based autopsy studies provide valuable insights into the causes of
dementia but are limited by sample size and restriction to specific populations …

Caffeic acid-based compounds possess a high degree of structural diversity and show a
variety of pharmacological properties, providing a useful framework for the discovery of new …