The role of artificial intelligence in deciphering diet–disease relationships: case studies

Y Cohen, R Valdés-Mas, E Elinav - Annual review of nutrition, 2023 - annualreviews.org
Modernization of society from a rural, hunter-gatherer setting into an urban and industrial
habitat, with the associated dietary changes, has led to an increased prevalence of …

Does voice matter? Investigating patient satisfaction on mobile health consultation

Y Liu, X Zhang, L Liu, K Lai - Information Processing & Management, 2023 - Elsevier
The rapid development of mobile technologies enables more patients to adopt mobile
consultations for health services. Mobile health consultations allow voice consultation, a …

[HTML][HTML] Source space connectomics of neurodegeneration: one-metric approach does not fit all

P Prado, S Moguilner, JA Mejía… - Neurobiology of …, 2023 - Elsevier
Brain functional connectivity in dementia has been assessed with dissimilar EEG
connectivity metrics and estimation procedures, thereby increasing results' heterogeneity. In …

Animal models of Alzheimer's disease: preclinical insights and challenges

QQ Xu, W Yang, M Zhong, ZX Lin, NE Gray… - Acta Materia …, 2023 - scienceopen.com
Alzheimer's disease (AD), an irreversible neurodegenerative disease that progressively
impairs memory and cognitive judgment, severely affects the quality of life and imposes a …

[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system

B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …

[HTML][HTML] Hyperoside alleviates toxicity of β-amyloid via endoplasmic reticulum-mitochondrial calcium signal transduction cascade in APP/PS1 double transgenic …

LL Song, YQ Qu, YP Tang, X Chen, HH Lo, LQ Qu… - Redox Biology, 2023 - Elsevier
Alzheimer's disease is a neurodegenerative disorder characterized by a decline in cognitive
function. The β-amyloid (Aβ) hypothesis suggests that Aβ peptides can spontaneously …

Butyrylcholinesterase inhibitors as potential anti-Alzheimer's agents: an updated patent review (2018-present)

JG Fernandez-Bolanos, O Lopez - Expert Opinion on Therapeutic …, 2022 - Taylor & Francis
Introduction Alzheimer's disease (AD) constitutes one of the most devastating diseases, with
an extraordinarily high increase expected for the next few years. Despite the numerous …

An update on toll-like receptor 2, its function and dimerization in pro-and anti-inflammatory processes

K Colleselli, A Stierschneider, C Wiesner - International Journal of …, 2023 - mdpi.com
While a certain level of inflammation is critical for humans to survive infection and injury, a
prolonged inflammatory response can have fatal consequences. Pattern recognition Toll-like …

Level of LncRNA GAS5 and hippocampal volume are associated with the progression of Alzheimer's disease

X Chen, G Ren, Y Li, W Chao, S Chen… - Clinical Interventions in …, 2022 - Taylor & Francis
Purpose We evaluated the diagnostic value of long non-coding RNA growth arrest-specific
transcript 5 (GAS5) and its relationship with hippocampal volume in Alzheimer's disease …

Nanomedicines for Alzheimer's disease: Therapies based on pathological mechanisms

G Cheng, A Xie, Z Yan, X Zhu, Y Song, T Chen - Brain‐X, 2023 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide.
Because of the complex pathogenesis of AD and the unique location of AD lesions, effective …