Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a
global health issue. A comprehensive understanding of the different molecular mechanisms …

abstract Poorly controlled asthma is especially common in low resource countries. Aside
from lack of access to, or poor technique with, inhaled beta-2 agonists and corticosteroids …

In the past 2 years, there continue to be advances in our understanding of the genetic and
epigenetic underpinnings of atopy pertaining to disease risk and disease severity. The joint …

Background Nonsteroidal anti-inflammatory drugs–exacerbated respiratory disease (N-
ERD) is currently classified as a type-2 (T2) immune-mediated disease characterized by …

Background Mucus plugs have been described in the airways of asthmatic subjects,
particularly those with associated with type 2 inflammation and sputum eosinophilia. In the …

Transcriptomics has revolutionized our understanding of the pathobiological heterogeneity
underlying complex allergic diseases, leading to both the discovery of multiple inflammatory …

Although substantial progress has been made in our understanding of asthma pathogenesis
and phenotypes over the 60-year history of Aspen Lung Conferences on asthma, many …

This is an exciting time to be conducting asthma research. The recent development of
targeted asthma biologics has validated the power of basic research to discover new …

We read with interest the study by Guntur et al 1 titled “Refractory neutrophilic asthma and
ciliary genes.” This article showed that the dysregulation and downregulation of ciliary …