[HTML][HTML] SARS-CoV-2 vaccines, vaccine development technologies, and significant efforts in vaccine development during the pandemic: the lessons learned might …

C Chakraborty, M Bhattacharya, K Dhama - Vaccines, 2023 - mdpi.com
We are currently approaching three years since the beginning of the coronavirus disease
2019 (COVID-19) pandemic. SARS-CoV-2 has caused extensive disruptions in everyday …

[HTML][HTML] Oral lesions associated with COVID-19 and the participation of the buccal cavity as a key player for establishment of immunity against SARS-CoV-2

JR Gutierrez-Camacho, L Avila-Carrasco… - International Journal of …, 2022 - mdpi.com
Background: Some oral lesions have been described in patients infected with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2); the possibility has been raised that the …

[HTML][HTML] Mucosal immune response after the booster dose of the BNT162b2 COVID-19 vaccine

L Azzi, D Dalla Gasperina, G Veronesi, M Shallak… - …, 2023 - thelancet.com
Background To date, only a few studies reported data regarding the development of
mucosal immune response after the BNT162b2-booster vaccination. Methods Samples of …

[HTML][HTML] Infection-or AZD1222 vaccine-mediated immunity reduces SARS-CoV-2 transmission but increases Omicron competitiveness in hamsters

JR Port, CK Yinda, JC Riopelle, ZA Weishampel… - Nature …, 2023 - nature.com
Limited data is available on the effect of vaccination and previous virus exposure on the
nature of SARS-CoV-2 transmission and immune-pressure on variants. To understand the …

[HTML][HTML] SARS-CoV-2: immunity, challenges with current vaccines, and a novel perspective on mucosal vaccines

R Sunagar, A Singh, S Kumar - Vaccines, 2023 - mdpi.com
The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …

[HTML][HTML] Oral delivery of mRNA vaccine by plant-derived extracellular vesicle carriers

MAC Pomatto, C Gai, F Negro, L Massari… - Cells, 2023 - mdpi.com
mRNA-based vaccines were effective in contrasting SARS-CoV-2 infection. However, they
presented several limitations of storage and supply chain, and their parenteral …

[HTML][HTML] Intranasal administration of adenoviral vaccines expressing SARS-CoV-2 spike protein improves vaccine immunity in mouse models

TL Freitag, R Fagerlund, NL Karam, VM Leppänen… - Vaccine, 2023 - Elsevier
The ongoing SARS-CoV-2 pandemic is controlled but not halted by public health measures
and mass vaccination strategies which have exclusively relied on intramuscular vaccines …

[HTML][HTML] SARS-CoV-2 Omicron variant shedding during respiratory activities

KS Tan, SWX Ong, MH Koh, DJW Tay, DZH Aw… - International Journal of …, 2023 - Elsevier
Objectives As the world transitions to COVID-19 endemicity, studies focusing on aerosol
shedding of highly transmissible SARS-CoV-2 variants of concern (VOCs) are vital for the …

[HTML][HTML] Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis

MJ Ruiz, G Siracusano… - Frontiers in …, 2022 - frontiersin.org
The role of the mucosal pulmonary antibody response in coronavirus disease 2019 (COVID-
19) outcome remains unclear. Here, we found that in bronchoalveolar lavage (BAL) samples …

[HTML][HTML] Protection from COVID-19 disease in hamsters vaccinated with subunit SARS-CoV-2 S1 mucosal vaccines adjuvanted with different adjuvants

Y Sui, H Andersen, J Li, T Hoang, Y Bekele… - Frontiers in …, 2023 - frontiersin.org
Introduction Adjuvant plays an important role in directing the immune responses induced by
vaccines. In previous studies, we have shown that a mucosal SARS-CoV-2 S1 subunit …