Sarcopenia, a geriatric syndrome that is characterized by a progressive and generalized
skeletal muscle disorder, can be associated with many comorbidities, including obesity …

Vaccination is one of medicine's greatest achievements; however, its full potential is
hampered by considerable variation in efficacy across populations and geographical …

Organismal ageing is associated with many physiological changes, including differences in
the immune system of most animals. These differences are often considered to be a key …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Aging is characterized by progressive loss of organ and tissue function, and the immune
system is no exception to that inevitable principle. Of all the age-related changes in the …

One of the traits of cancer cells is abnormal DNA methylation patterns. The idea that age-
related epigenetic changes may partially explain the increased risk of cancer in the elderly is …

The phenomenon of accumulation of senescent adaptive immunity cells in the elderly is
attracting attention due to the increasing risk of global epidemics and aging of the global …

Background Melanoma disease patterns vary with patient age. Aim To evaluate sentinel
lymph node biopsy (SLNB) in managing melanoma at differing patient ages. Methods Online …

The aging process can have detrimental effects on the immune system rendering the elderly
more susceptible to infectious disease and less responsive to vaccination. Major depressive …

Cellular senescence—the irreversible cell cycle arrest driven by a variety of mechanisms
and, more specifically, the senescence-associated secretory phenotype (SASP)—is an …