Aging is a complex process strongly determined by genetics. Previous reports have shown
that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy …

Fifteen years ago, the question “Why do we lose the war on cancer?” sounded (1). After an
interview with the world's leading oncologists, the author presented, in particular …

EvALUATING the effect of any intervention that influences aging requires some sort of
endpoint to be measured, ideally life span. Maximum life span is the key outcome influenced …

This study defines and estimates the metabolite-lipidic component association networks
constructed from an array of 20 metabolites and 114 lipids identified and quantified via NMR …

Recently there is a growing interest for the study of the molecular basis of ageing processes
and on the differences among genders. These studies require many data, models and tools …

Abstract African green monkeys (AGMs, Chlorocebus aethiops) are Old World monkeys
which are used as experimental models in biomedical research. Recent technological …

Background Aging is broadly considered to be a dynamic process that accumulates
unfavourable structural and functional changes in a time dependent fashion, leading to a …

Osteoarthritis (OA) is the most common form of arthritis affecting more than 12% of people
over the age of 60. 1 Although late-onset articular cartilage degeneration is common and …

Abstract By 2050, population aged> 65 years is expected to be more than 2.5 times that of
the population aged 0–4 years. The onset of age-related ailments, such as …

Immunosenescence is the general term used to describe the aging-associated decline of
immunological function that explains the higher susceptibility to infectious diseases and …