The microbiome and gut homeostasis

JY Lee, RM Tsolis, AJ Bäumler - Science, 2022 - science.org
Changes in the composition of the gut microbiota are associated with many human
diseases. So far, however, we have failed to define homeostasis or dysbiosis by the …

Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis

J Cai, H Chen, M Lu, Y Zhang, B Lu, L You, T Zhang… - Cancer letters, 2021 - Elsevier
Pancreatic cancer is a malignancy with poor prognosis and high mortality. The recent
increase in pancreatic cancer incidence and mortality has resulted in an increased number …

Growth factors, PI3K/AKT/mTOR and MAPK signaling pathways in colorectal cancer pathogenesis: where are we now?

C Stefani, D Miricescu, II Stanescu-Spinu… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a predominant malignancy worldwide, being the fourth most
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …

Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors

P Rawla, T Sunkara, A Barsouk - Gastroenterology Review/Przegląd …, 2019 - termedia.pl
According to GLOBOCAN 2018 data, colorectal cancer (CRC) is the third most deadly and
fourth most commonly diagnosed cancer in the world. Nearly 2 million new cases and about …

An umbrella review of the evidence associating diet and cancer risk at 11 anatomical sites

N Papadimitriou, G Markozannes… - Nature …, 2021 - nature.com
There is evidence that diet and nutrition are modifiable risk factors for several cancers, but
associations may be flawed due to inherent biases. Nutritional epidemiology studies have …

Cancer and Mediterranean diet: a review

MC Mentella, F Scaldaferri, C Ricci, A Gasbarrini… - Nutrients, 2019 - mdpi.com
The Mediterranean diet is considered one of the most worldwide healthy dietary patterns
thanks to a combination of foods rich mainly in antioxidants and anti-inflammatory nutrients …

Influence of the gut microbiome, diet, and environment on risk of colorectal cancer

M Song, AT Chan, J Sun - Gastroenterology, 2020 - Elsevier
Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

The intestinal microbiota in colorectal cancer

H Tilg, TE Adolph, RR Gerner, AR Moschen - Cancer cell, 2018 - cell.com
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …

[PDF][PDF] Risk factors for colorectal polyps and cancer

JA Sninsky, BM Shore, GV Lupu, SD Crockett - … Endoscopy Clinics of North …, 2022 - Elsevier
The strongest nonmodifiable risk factors for CRC and precancerous polyps are age, male
sex, and family history of CRC. Current evidence indicates that smoking, obesity, and diet …

Gastrointestinal cancers in China, the USA, and Europe

Y Xie, L Shi, X He, Y Luo - Gastroenterology report, 2021 - academic.oup.com
Gastrointestinal (GI) cancers, including colorectal cancer, gastric cancer, and esophageal
cancer, are a major medical and economic burden worldwide and have the largest number …