[HTML][HTML] Lessons from the host defences of bats, a unique viral reservoir

AT Irving, M Ahn, G Goh, DE Anderson, LF Wang - Nature, 2021 - nature.com
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …

[HTML][HTML] Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

[HTML][HTML] Towards complete and error-free genome assemblies of all vertebrate species

A Rhie, SA McCarthy, O Fedrigo, J Damas, G Formenti… - Nature, 2021 - nature.com
High-quality and complete reference genome assemblies are fundamental for the
application of genomics to biology, disease, and biodiversity conservation. However, such …

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

J Damas, GM Hughes, KC Keough… - Proceedings of the …, 2020 - National Acad Sciences
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of COVID-19. The main receptor of SARS-CoV-2, angiotensin I converting enzyme …

[HTML][HTML] DNA methylation predicts age and provides insight into exceptional longevity of bats

GS Wilkinson, DM Adams, A Haghani, AT Lu… - Nature …, 2021 - nature.com
Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

[HTML][HTML] Universal nomenclature for oxytocin–vasotocin ligand and receptor families

C Theofanopoulou, G Gedman, JA Cahill, C Boeckx… - Nature, 2021 - nature.com
Oxytocin (OXT; hereafter OT) and arginine vasopressin or vasotocin (AVP or VT; hereafter
VT) are neurotransmitter ligands that function through specific receptors to control diverse …

[HTML][HTML] A beginner's guide to manual curation of transposable elements

C Goubert, RJ Craig, AF Bilat, V Peona, AA Vogan… - Mobile DNA, 2022 - Springer
Background In the study of transposable elements (TEs), the generation of a high
confidence set of consensus sequences that represent the diversity of TEs found in a given …

Integrating gene annotation with orthology inference at scale

BM Kirilenko, C Munegowda, E Osipova, D Jebb… - Science, 2023 - science.org
Annotating coding genes and inferring orthologs are two classical challenges in genomics
and evolutionary biology that have traditionally been approached separately, limiting …

A complete, telomere-to-telomere human genome sequence presents new opportunities for evolutionary genomics

Y Mao, G Zhang - Nature methods, 2022 - nature.com
The release of the first telomere-to-telomere (T2T) human genome sequence marks a
milestone for human genomics research and holds promise of complete genomes for …

[HTML][HTML] SARS-CoV-2 variants evolved during the early stage of the pandemic and effects of mutations on adaptation in Wuhan populations

A Awadasseid, Y Wu, Y Tanaka… - International journal of …, 2021 - ncbi.nlm.nih.gov
The outbreak of the coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The pandemic apparently started in …