Cellular senescence entails a permanent proliferative arrest, coupled to multiple phenotypic
changes. Among these changes is the release of numerous biologically active molecules …

Extending healthspan is a major public health challenge. Diet is one of the modifiable
factors for preventing age-related diseases and preserving overall good health status during …

The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Does the quality of our diet during early life impact our long-term mental health?
Accumulating evidence suggests that nutrition interacts with our genes and that there is a …

Neural degeneration is a hallmark of healthy aging and can be associated with specific
cognitive impairments. However, neural degeneration per se is not matched by unremitting …

Physical activity and diet are essential for maintaining good health and preventing the
development of non-communicable diseases, especially in the older adults. One aspect that …

Appetite loss/anorexia of aging is a highly prevalent and burdensome geriatric syndrome
that strongly impairs the quality of life of older adults. Loss of appetite is associated with …

Background Quantitative attribution of the burden of disease due to population aging is an
important part of setting meaningful global health priorities. This study comprehensively …

Aging is characterized by significant physiological changes, with the degree of decline
varying significantly among individuals. The preservation of intrinsic capacity over the …

Background Dysphagia is common in elderly patients with dementia and is one of the
common clinical geriatric syndromes. It imposes a heavy burden on patients and their …