Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …

Since the discovery of transposons, their sheer abundance in host genomes has puzzled
many. While historically viewed as largely harmless 'parasitic'DNAs during evolution …

Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

The global diversity of fungi has been estimated using several different approaches. There is
somewhere between 2–11 million estimated species, but the number of formally described …

Summary H3K9me3, as a hallmark of heterochromatin, is important for cell-fate specification.
However, it remains unknown how H3K9me3 is reprogrammed during human early embryo …

Understanding the regulatory landscape of the human genome is a long-standing objective
of modern biology. Using the reference-free alignment across 241 mammalian genomes …

Repetitive DNA sequences playing critical roles in driving evolution, inducing variation, and
regulating gene expression. In this review, we summarized the definition, arrangement, and …

Embryo implantation in humans is interstitial, meaning the entire conceptus embeds in the
endometrium before the placental trophoblast invades beyond the uterine mucosa into the …

We examined transposable element (TE) content of 248 placental mammal genome
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …

Cys2-His2 zinc finger genes (ZNFs) form the largest family of transcription factors in
metazoans. ZNF evolution is highly dynamic and characterized by the rapid expansion and …