Artemisinins are the cornerstone of anti-malarial drugs. Emergence and spread of resistance to them,, raises risk of wiping out recent gains achieved in reducing worldwide malaria …
Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant …
Artemisinin partial resistance may facilitate selection of Plasmodium falciparum resistant to combination therapy partner drugs. We evaluated 99 P. falciparum isolates collected in 2021 …
The emergence of mutant K13-mediated artemisinin (ART) resistance in Plasmodium falciparum malaria parasites has led to widespread treatment failures across Southeast …
We report a large multicenter genome-wide association study of Plasmodium falciparum resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast …
C Amaratunga, P Lim, S Suon, S Sreng… - The Lancet infectious …, 2016 - thelancet.com
Summary Background Artemisinin resistance in Plasmodium falciparum threatens to reduce the efficacy of artemisinin combination therapies (ACTs), thus compromising global efforts to …
A Monroe, NA Williams, S Ogoma, C Karema, F Okumu - Malaria Journal, 2022 - Springer
Abstract The World Malaria Report, released in December 2021, reflects the unique challenges currently facing the global malaria community. The report showed the …
R Amato, P Lim, O Miotto, C Amaratunga… - The Lancet Infectious …, 2017 - thelancet.com
Background As the prevalence of artemisinin-resistant Plasmodium falciparum malaria increases in the Greater Mekong subregion, emerging resistance to partner drugs in …
JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community alike, and while the general notion of an excessive or uncontrolled release of …