The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …

The role of the microbiome in human aging is important: the microbiome directly impacts
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …

Recently, the gut microbiota (GM) has been shown to be a regulator of bone homeostasis
and the mechanisms by which GM modulates bone mass are still being investigated. Here, it …

As the global population becomes older, understanding the impact of aging on health and
disease becomes paramount. Recent advancements in multiomic technology have allowed …

The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …

Aging-related salivary dysfunction commonly induces the poor oral health, including
decreased saliva flow and dental caries. Although the clinical significance of the salivary …

Accumulation of misfolded protein aggregates is a hallmark event in many age-related
protein misfolding disorders, including some of the most prevalent and insidious …

The interplay between microbiota and host metabolism plays an important role in health.
Here, we examined the relationship between age, gut microbiome and host serum …

Aging is a natural biological event that has some downsides such as increased frailty,
decline in cognitive and physical functions leading to chronical diseases, and lower quality …