AI in health and medicine
Artificial intelligence (AI) is poised to broadly reshape medicine, potentially improving the
experiences of both clinicians and patients. We discuss key findings from a 2-year weekly …
experiences of both clinicians and patients. We discuss key findings from a 2-year weekly …
Liquid biopsy: from discovery to clinical application
C Alix-Panabières, K Pantel - Cancer discovery, 2021 - AACR
Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA)
have received enormous attention as new biomarkers and subjects of translational research …
have received enormous attention as new biomarkers and subjects of translational research …
[HTML][HTML] Current cancer burden in China: epidemiology, etiology, and prevention
Cancer has become the most common cause of death in China. Owing to rapid economic
development, improved livelihood, and shifts in risk factors, cancer epidemiology has …
development, improved livelihood, and shifts in risk factors, cancer epidemiology has …
ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …
Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer
H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
DNA methylation-based predictors of health: applications and statistical considerations
DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …
development, because, unlike static genetic risk estimates, DNA methylation varies …
Circulating tumour cells for early detection of clinically relevant cancer
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …
detection are paramount to reducing cancer-related deaths and improving patient outcomes …
Liquid biopsy of methylation biomarkers in cell-free DNA
H Luo, W Wei, Z Ye, J Zheng, R Xu - Trends in molecular medicine, 2021 - cell.com
Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …
Liquid biopsies: Potential and challenges
I Heidrich, L Ačkar… - … Journal of Cancer, 2021 - Wiley Online Library
The analysis of tumor cells or tumor cell products obtained from blood or other body fluids
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …
[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …