Colorectal cancer (CRC) is one of the most common human malignancies accounting for
approximately 10% of worldwide cancer incidence and mortality. While early-stage CRC is …

The volume and complexity of scientific and clinical data in oncology have grown markedly
over recent years, including but not limited to the realms of electronic health data …

Abstract The role of Artificial Intelligence and Machine Learning in cancer research offers
several advantages, primarily scaling up the information processing and increasing the …

DNA methylation profiles are in dynamic equilibrium via the initiation of methylation,
maintenance of methylation and demethylation, which control gene expression and …

Background In non-metastatic colorectal cancer (CRC), we evaluated prospectively the
pertinence of longitudinal detection and quantification of circulating tumor DNA (ctDNA) as a …

Tumor-derived circulating cell-free DNA (cfDNA) provides critical clues for cancer early
diagnosis, yet it often suffers from low sensitivity. Here, we present a cancer early diagnosis …

In the era of precision oncology, use of circulating tumor DNA (ctDNA) is emerging as a
minimally invasive approach for the diagnosis and management of patients with cancer and …

Despite major therapeutic progress, most advanced solid tumors are still incurable. Cancer
interception is the active way to combat cancer onset, and development of this approach …

Methylation analysis of circulating cell-free DNA (cirDNA), as a liquid biopsy, has a
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …

Early detection is crucial to improve breast cancer (BC) patients' outcomes and survival.
Mammogram and ultrasound adopting the Breast Imaging Reporting and Data System (BI …