M Vacante, R Ciuni, F Basile, A Biondi - Biomedicines, 2020 - mdpi.com
Currently, there is a crucial need for novel diagnostic and prognostic biomarkers with high specificity and sensitivity in patients with colorectal cancer. A “liquid biopsy” is characterized …
Long‐read sequencing (LRS) has been around for more than a decade, but widespread adoption of the technology has been slow due to the perceived high error rates and high …
L Liang, Y Zhang, C Li, Y Liao, G Wang, J Xu, Y Li… - …, 2022 - thelancet.com
Background Plasma cell-free DNA (cfDNA) methylation has shown the potential in the detection and prognostic testing in multiple cancers. Herein, we thoroughly investigate the …
Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the second in terms of mortality. Recent studies have shown that various proteins, such as …
K Chen, G Kang, Z Zhang, A Lizaso, S Beck, I Lyskjær… - BMC medicine, 2023 - Springer
Background The feasibility of DNA methylation-based assays in detecting minimal residual disease (MRD) and postoperative monitoring remains unestablished. We aim to investigate …
X Li, AS Kulkarni, X Liu, WQ Gao, L Huang… - Small …, 2021 - Wiley Online Library
Colorectal cancer (CRC) is the third most common fatal cancer worldwide, accounting for≈ 10% of cancer‐related mortality. Metabolic shift occurs from the very early stage during the …
X Wen, H Pu, Q Liu, Z Guo, D Luo - Cancers, 2022 - mdpi.com
Simple Summary ctDNA is a small DNA fragment derived from tumor cells, which contains tumor-related genomic information, such as mutation, methylation, microsatellite instability …
Y Xie, P Li, D Sun, Q Qi, S Ma, Y Zhao, S Zhang… - Cancer Research, 2023 - AACR
An effective blood-based method for the diagnosis of colorectal cancer has not yet been developed. Molecular alterations of immune cells occur early in tumorigenesis, providing the …
AK Angeles, F Janke, S Bauer, P Christopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Liquid biopsies provide a non-invasive means to diagnose and profile tumors when tissue is not available. Sequence-based analysis of cell-free DNA (cfDNA) is …