Circulating tumor DNA (ctDNA) carries tumor-specific genetic and epigenetic variations. To
identify extranodal natural killer/T cell lymphoma (ENKTL)-specific methylation markers and …

Colorectal cancer (CRC) is the most frequently occurring malignancy in the world. However,
the mortality from CRC can be reduced through early diagnostics, selection of the most …

Over the past two decades, liquid biopsy has been increasingly used as a supplement, or
even, a replacement to the traditional biopsy in clinical oncological practice, due to its …

Colorectal cancer (CRC) is the third most common cancer with the second most frequent
cause of death worldwide. One fourth to one fifth of the CRC cases are detected at advance …

The complex mechanisms of ageing biology are increasingly understood. Interventions to
reduce or delay ageing‐associated diseases are emerging. Cancer is one of the diseases …

Purpose More than 99% of cervical cancers and up to 40% of vulvar cancers are human
papillomavirus (HPV) related. HPV 16 and 18 are the most relevant subtypes. Novel …

Background: Hepatocellular carcinoma (HCC) is a prevalent malignancy with a high
mortality rate. Cellular senescence, an irreversible state of cell cycle arrest, plays a …

Colorectal carcinoma (CRC) is characterized by wide intratumor heterogeneity with general
genomic instability and there is a need for improved diagnostic, prognostic, and therapeutic …

Epigenetic clocks are accurate predictors of human chronological age based on the analysis
of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison …

Background Early detection of colorectal carcinoma (CRC) would help to identify tumors
when curative treatments are available and beneficial. However, current screening methods …