Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …

Alterations in microbiota of patients with COVID-19: potential mechanisms and therapeutic interventions

B Wang, L Zhang, Y Wang, T Dai, Z Qin… - Signal transduction and …, 2022 - nature.com
The global coronavirus disease 2019 (COVID-19) pandemic is currently ongoing. It is
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A high …

Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial

P Gutiérrez-Castrellón, T Gandara-Martí… - Gut …, 2022 - Taylor & Francis
Intestinal bacteria may influence lung homeostasis via the gut-lung axis. We conducted a
single-center, quadruple-blinded, randomized trial in adult symptomatic Coronavirus …

[HTML][HTML] Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events

SC Ng, Y Peng, L Zhang, CKP Mok, S Zhao, A Li… - Gut, 2022 - gut.bmj.com
Objective The gut microbiota plays a key role in modulating host immune response. We
conducted a prospective, observational study to examine gut microbiota composition in …

Vaccination in patients with kidney failure: lessons from COVID-19

N Babel, C Hugo, TH Westhoff - Nature Reviews Nephrology, 2022 - nature.com
Infection is the second leading cause of death in patients with chronic kidney disease (CKD).
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …

[PDF][PDF] Metabolic programs tailor T cell immunity in viral infection, cancer, and aging

SH Møller, PC Hsueh, YR Yu, L Zhang, PC Ho - Cell metabolism, 2022 - cell.com
Productive T cell responses to infection and cancer rely on coordinated metabolic
reprogramming and epigenetic remodeling among the immune cells. In particular, T cell …

Host factors and vaccine efficacy: Implications for COVID‐19 vaccines

S Falahi, A Kenarkoohi - Journal of medical virology, 2022 - Wiley Online Library
The efficacy of the vaccines varies between individuals and populations. The
immunogenicity of the vaccine is influenced by various factors, including host factors …

Microbiota regulation of viral infections through interferon signaling

NI Wirusanti, MT Baldridge, VC Harris - Trends in microbiology, 2022 - cell.com
The interferon (IFN) response is the major early innate immune response against invading
viral pathogens and is even capable of mediating sterilizing antiviral immunity without the …

Risk of Alzheimer's disease following influenza vaccination: a claims-based cohort study using propensity score matching

AS Bukhbinder, Y Ling, O Hasan… - Journal of …, 2022 - content.iospress.com
Background: Prior studies have found a reduced risk of dementia of any etiology following
influenza vaccination in selected populations, including veterans and patients with serious …

Lipopolysaccharide and the gut microbiota: considering structural variation

AE Mohr, M Crawford, P Jasbi, S Fessler… - FEBS …, 2022 - Wiley Online Library
Systemic inflammation is associated with chronic disease and is purported to be a main
pathogenic mechanism underlying metabolic conditions. Microbes harbored in the host …