The value of SARS-CoV-2 lateral flow immunoassay (LFIA) tests for estimating individual
disease risk is unclear. The REACT-2 study in England, UK, obtained self-administered …

Following the COVID-19 pandemic, novel vaccines have successfully reduced severe
disease and death. Despite eliciting lower antibody responses, adenoviral vector vaccines …

The humoral response after the fourth dose of a mRNA vaccine against COVID-19 has not
been adequately described in elderly recipients, particularly those not exposed previously to …

A multitude of alterations in the old immune system impair its functional integrity. Closely
related, older individuals show, for example, a reduced responsiveness to severe acute …

Abstract Background Coronavirus disease 2019 (COVID-19) remains a threat to vulnerable
populations such as long-term care facility (LTCF) residents, who are often older, severely …

Objectives The COVID-19 pandemic has revealed significant differences in COVID-19
vaccination rates, with African Americans reporting lower rates compared to other racial and …

Background To improve the assessment of COVID-19 vaccine use, safety, and effectiveness
in older adults and persons with complex multimorbidity, the COVid VAXines Effects on the …

Background Vaccines and vaccine boosting have blunted excess morbidity and mortality
from SARS-CoV-2 infection suffered by older nursing home residents (NHR). However, the …

Background Understanding the immune response kinetics to SARS-CoV-2 infection and
COVID-19 vaccination is important in nursing home (NH) residents, a high-risk population …

At the start of the pandemic, it became evident that older adults were most likely to develop
severe COVID-19 infection when exposed to the SARS-CoV-2 virus. Although chronological …