Cancer metastasis is no longer viewed as a linear cascade of events but rather as a series
of concurrent, partially overlapping processes, as successfully metastasizing cells assume …

Introduction: Early detection of cancers through the analysis of ctDNA could have a
significant impact on morbidity and mortality of cancer patients. However, using ctDNA for …

Sporadic colorectal cancer (CRC) is a result of complex interactions between the host and
its environment. Environmental stressors act by causing host cell DNA alterations implicated …

Objective Mutations in cell-free circulating DNA (cfDNA) have been studied for tracking
disease relapse in colorectal cancer (CRC). This approach requires personalised assay …

BACKGROUND In nonmetastatic triple-negative breast cancer (TNBC) patients, we
investigated whether circulating tumor DNA (ctDNA) detection can reflect the tumor …

Purpose: Markers of chemotherapy efficacy in metastatic colorectal cancer (mCRC) are
essential for optimization of treatment strategies. We evaluated the applicability of early …

The clinical management of cancer has evolved in recent years towards more personalized
strategies that require a comprehensive knowledge of the complex molecular features …

Abstract Purpose: Circulating tumor DNA (ctDNA) has been suggested as a major
prognostic factor in resected stage-III colon cancer. We analyzed ctDNA of patients …

Background RAS mutations are currently sought for in tumor samples, which takes a median
of almost 3 weeks in western European countries. This creates problems in clinical …

The innovation of liquid biopsy holds great potential to revolutionise cancer management
through early diagnosis and timely treatment of cancer. Integrative analysis of different …